Vascular Ehlers-Danlos syndrome (vEDS) is a rare genetic disorder characterized by fragile blood vessels, skin that is easily bruised, and a heightened risk of internal bleeding and other vascular complications. Managing vEDS requires a comprehensive approach, as there is currently no cure for the condition. Treatment typically focuses on symptom management and prevention of complications. While there are no specific medications for vEDS, healthcare providers may prescribe pain relievers, blood pressure medications, and other supportive therapies to reduce cardiovascular risks and enhance quality of life. Understanding the available treatment options and the importance of regular monitoring is crucial for individuals living with vEDS and their healthcare teams to ensure optimal care and management of this challenging condition.