Purixan is called Xaluprine in Europe.
Information about Purixan Oral Suspension (Mercaptopurine)
Purixan Oral Suspension (Mercaptopurine) is a liquid form of the chemotherapy drug mercaptopurine. It is used to treat specific types of cancers and autoimmune conditions by suppressing the immune system or inhibiting the growth of cancer cells. The oral suspension form makes it easier for individuals who have difficulty swallowing tablets, such as children or patients with certain medical conditions, to take the medication.
Product Highlights
- It is commonly used as part of the chemotherapy regimen to treat ALL, particularly in pediatric and adult patients.
- Purixan can be used for conditions like Crohn's disease and ulcerative colitis, where it helps control the immune response that causes inflammation in the intestines.
- It may be prescribed for other autoimmune disorders at the discretion of a healthcare provider.
Key Ingredient
Key Benefits
- Purixan is a key part of chemotherapy protocols for treating acute lymphoblastic leukemia (ALL), contributing to higher survival rates.
- It helps reduce excessive immune activity in autoimmune diseases like Crohn’s disease and ulcerative colitis, helping to manage symptoms and inflammation.
- The oral suspension form of mercaptopurine offers a more flexible option for patients who have difficulty swallowing tablets, such as children or those with swallowing issues.
Direction of Use
- Purixan Oral Suspension should be taken exactly as prescribed by a healthcare provider.
- The typical dosage depends on the patient's weight, the condition being treated, and the treatment plan.
- The oral suspension is typically taken once or twice daily, with or without food.
- Patients should use the provided dosing syringe to ensure accurate measurement of the liquid.
- The suspension should be shaken well before each dose to ensure proper mixing.
- Regular blood tests are needed during treatment to monitor liver function and blood cell counts, as Purixan can affect these parameters.
Safety Concerns
- Mercaptopurine can cause liver damage, so liver function tests should be monitored regularly throughout treatment.
- Purixan may decrease blood cell production, which can increase the risk of infections, anemia, and bleeding.
- As an immunosuppressive drug, Purixan increases the risk of infections, which may require prompt treatment if any symptoms occur.
- Common side effects may include nausea, vomiting, decreased appetite, and fatigue. Serious side effects include pancreatitis, gastrointestinal problems, and severe bone marrow suppression.
- Purixan may interact with other medications, such as allopurinol (used to treat gout), increasing the risk of side effects.
Avoid Purixan Oral Suspension (Mercaptopurine) If
- Individuals who are allergic to mercaptopurine or any components of Purixan should not take this medication.
- Purixan is contraindicated in patients with severe liver impairment, as it can worsen liver function.
- Due to its immunosuppressive effects, Purixan should be avoided in patients with active infections or a history of recurrent infections unless supervised by a doctor.
- Mercaptopurine is classified as a Category D medication, meaning it can harm a developing fetus. It is generally advised to avoid use during pregnancy unless the benefits outweigh the potential risks. Women should avoid pregnancy while taking Purixan.
- Purixan is not recommended during breastfeeding, as it may transfer into breast milk and potentially harm the infant.
