Rheumatrex is called Maxtrex in Europe.
Information about Rheumatrex (Methotrexate)
Rheumatrex (Methotrexate) is a prescription medication used primarily for treating autoimmune conditions and certain types of cancer. Methotrexate is an immunosuppressive drug that works by inhibiting the growth of rapidly dividing cells, such as those involved in the inflammatory process in conditions like rheumatoid arthritis and psoriasis, as well as cancerous cells in certain cancers.
Product Highlights
- Used to reduce inflammation and damage caused by autoimmune activity in the joints.
- For severe cases that do not respond to topical treatments.
- Includes certain cancers like leukemia, lymphoma, and breast cancer, where methotrexate targets cancerous cells.
- Such as Crohn’s disease and lupus, when standard treatments are insufficient.
Key Ingredient
Key Benefits
- In autoimmune diseases like rheumatoid arthritis, it helps to control excessive inflammation.
- In conditions such as rheumatoid arthritis and psoriasis, it can slow or halt the progression of the disease.
- It interferes with the growth of cancer cells, particularly in certain types of leukemia and lymphomas.
- Available both orally and by injection, making it adaptable for different patient needs.
Direction of Use
- Typically taken once weekly for conditions like rheumatoid arthritis, though the dosage may vary based on the severity of the condition.
- May be used when oral administration is not appropriate, often administered under the supervision of a healthcare professional.
- The exact dosage and frequency depend on the specific condition being treated and the patient’s individual response. For autoimmune conditions, lower doses are generally used than for cancer treatments.
Safety Concerns
- Methotrexate can cause liver toxicity, so regular liver function tests are recommended.
- It may suppress bone marrow, leading to decreased red blood cells, white blood cells, and platelets, increasing the risk of infections, anemia, and bleeding.
- Nausea, vomiting, and ulcers can occur, especially with high doses.
- Methotrexate is contraindicated during pregnancy due to potential harm to the fetus, and it is also not recommended for breastfeeding.
- Methotrexate may interact with other medications, such as NSAIDs, antibiotics, and other immunosuppressants, increasing the risk of toxicity.
Avoid Rheumatrex (Methotrexate) If
- Methotrexate is teratogenic (can cause birth defects) and should not be used by pregnant women or women planning to become pregnant.
- Methotrexate is excreted in breast milk and should be avoided by breastfeeding mothers.
- Individuals with pre-existing liver conditions (such as cirrhosis or hepatitis) should avoid methotrexate due to the risk of liver toxicity.
- Patients with severely impaired kidney function should avoid this medication as it can further damage kidney function.
- Methotrexate can suppress the immune system, so it should not be used in individuals with active infections, as it may worsen the condition.
- Those with a known allergy to methotrexate or any of its ingredients should not take this medication.
