Tafinlar (Dabrafenib)

Brand Options

arrow pointer

Brand Name : Tafinlar

Marketing Authorization Holder : Novartis

Prescription Required

 
 
No Generic Medicine available for this medicine.

Product Details

Tafinlar

Save up to 65% with Tafinlar from Spain (called Rafinlar)

Available in English packaging for immediate delivery.

Information about Tafinlar (Dabrafenib)

Tafinlar (generic name: Dabrafenib) is a prescription medication that is primarily used to treat certain types of cancer. It is an oral drug that works by inhibiting the activity of the mutated BRAF protein, which is responsible for the growth and spread of cancer cells in certain cancers, particularly those with a BRAF V600E mutation. Tafinlar is often used in combination with other medications to improve treatment efficacy.

Product Highlights

  • Tafinlar is approved for the treatment of unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, either alone or in combination with trametinib.
  • For metastatic NSCLC with a BRAF V600E mutation.
  • Tafinlar is also indicated for the treatment of ATC with BRAF V600E mutation.
  • It is used in other cancers where the BRAF mutation plays a role in cancer growth.

Key Ingredient:

  • Dabrafenib

Key Benefits

  • Tafinlar specifically targets the BRAF mutation, which is found in various types of cancer. This targeted approach can help inhibit cancer cell growth and survival.
  • When combined with trametinib (another targeted therapy), Tafinlar has shown enhanced effectiveness in treating cancers with BRAF mutations.
  • In clinical trials, Tafinlar has been shown to significantly improve progression-free survival in patients with BRAF-mutant melanoma and other cancers.

Direction of Use

  • Tafinlar is typically taken as a capsule once or twice daily, depending on the specific cancer type and treatment plan.
  • Capsules should be swallowed whole, and the dosage will depend on individual patient factors such as cancer type and severity.
  • For certain indications, Tafinlar is used in combination with trametinib (a MEK inhibitor) for better results.

Safety Concerns

  • Common side effects may include fever, tiredness, headache, rash, nausea, vomiting, joint discomfort, and muscle aches. 
  • Potential serious side effects include heart problems, eye problems (e.g., eye pain, vision problems), skin issues (e.g., new or worsening skin cancers), and liver problems.
  • Regular monitoring is required, especially for liver function, heart health, and the presence of any new skin growths.

Avoid Tafinlar (Dabrafenib) If

  • Tafinlar may harm an unborn baby, and it is not recommended during pregnancy. It is important to use effective birth control during treatment and for a period afterward.
  • If you have a known allergy to Dabrafenib, you should not use Tafinlar.
  • Patients with severe liver problems should avoid this medication, as it may worsen liver function.
  • If you have heart conditions such as QT prolongation, you should avoid using Tafinlar without consulting your healthcare provider.
  • Tafinlar may interact with other medications, so it is essential to avoid using it in combination with drugs that may increase the risk of severe side effects or interfere with its action.


Image Image Image Image