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Tykerb is called Tyverb in Europe.
Information about Tykerb (Lapatinib)
Tykerb (Lapatinib) is an oral medication used to treat advanced or metastatic breast cancer that is HER2-positive. Lapatinib is a tyrosine kinase inhibitor, meaning it blocks the HER2 receptor, which is involved in the growth and spread of cancer cells. By targeting and inhibiting this pathway, Tykerb helps to slow or stop the growth of cancer cells in patients with HER2-positive breast cancer.
Product Highlights
- Tykerb is indicated for the treatment of advanced or metastatic breast cancer that is HER2-positive, which means the cancer cells have excess amounts of the HER2 protein.
- It is typically used in combination with other therapies, like capecitabine or letrozole, for patients whose cancer has not responded to other treatments.
Key Ingredient
Key Benefits
- Lapatinib specifically targets the HER2 receptor, making it effective in treating HER2-positive cancers.
- Tykerb is an oral medication, providing a convenient alternative to intravenous chemotherapy.
- Tykerb can be used in combination with other medications, helping to enhance the effectiveness of cancer treatment and potentially improving patient outcomes.
- In clinical trials, Tykerb has shown to slow down the progression of advanced breast cancer and may extend survival in certain patients.
Direction of Use
- Tykerb is typically taken once daily, with or without food. The standard dose is usually 1,250 mg per day, but this can vary depending on the treatment regimen and combination with other drugs.
- It's crucial to adhere to the prescribed dosage and schedule for administration. Tykerb is often used in combination with other medications like capecitabine or letrozole.
- It’s advised to swallow the tablet whole, without crushing or breaking it, to ensure proper absorption and effectiveness.
Safety Concerns
- A common side effect of Tykerb, which can sometimes be severe. It is important to manage diarrhea early to prevent dehydration.
- Tykerb can cause liver problems, including liver enzyme elevations. Liver function should be monitored during treatment.
- Tykerb may cause heart problems, particularly in patients with pre-existing heart conditions. Monitoring of heart function is recommended.
- Tykerb may interact with other medications, so patients should inform their healthcare provider about all drugs they are taking.
- Other side effects may include nausea, vomiting, and fatigue.
Avoid Tykerb (Lapatinib) If
- Tykerb should not be used in patients with severe liver dysfunction due to the risk of further liver complications.
- If you have an allergy to the drug, Tykerb should be avoided.
- Tykerb can harm an unborn baby and pass into breast milk, so it should be avoided during pregnancy and breastfeeding unless absolutely necessary and prescribed by a healthcare provider.
- If you have a history of heart problems, particularly heart failure or arrhythmias, Tykerb may not be appropriate for you.
