Xermelo (Telotristat)

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Brand Name : Xermelo

Marketing Authorization Holder : Lexicon Pharmaceuticals

Prescription Required

 
 
No Generic Medicine available for this medicine.

Product Details

Xermelo

Save 60% with Xermelo from Europe.

Non-english packaging - English label and English insert included. Plan in advance - allow us 7 days to ship your medicine

Manufacturer for Europe Tjoapack Netherlands B.V. Nieuwe Donk 9 4879 AC Etten-Leur Netherlands

Information about Xermelo (Telotristat)

Xermelo is a prescription medication used to treat the symptoms of carcinoid syndrome, a condition caused by carcinoid tumors that release large amounts of serotonin, leading to severe diarrhea. Telotristat, the active ingredient in Xermelo, works by inhibiting the production of serotonin in the intestines, helping to control diarrhea associated with this condition. Xermelo is typically prescribed when other treatments have not been effective.

Product Highlights

  • Xermelo is primarily used to treat diarrhea associated with carcinoid syndrome in adults. It is typically prescribed when other treatments, such as somatostatin analogs, have not sufficiently controlled symptoms.

Key Ingredient

  • Telotristat 

Key Benefits

  • Xermelo has been shown to significantly reduce the frequency of diarrhea in patients with carcinoid syndrome, improving quality of life.
  • By directly inhibiting serotonin production, it helps address the underlying cause of diarrhea in carcinoid syndrome.
  • Xermelo is typically used alongside somatostatin analogs to control symptoms, offering a dual approach to managing carcinoid syndrome.

Direction of Use

  • The usual dose is 250 mg taken orally three times a day with food.
  • Take the tablets with food and swallow them whole without chewing. 
  • For best results, take Xermelo consistently as prescribed. Do not change the dose without first consulting your healthcare provider. 

Safety Concerns

  • Some patients may experience gastrointestinal side effects like nausea, constipation, or abdominal pain. These side effects are usually mild, but they should still be monitored. 
  • Xermelo may cause liver enzyme changes in some patients. Your healthcare provider may monitor liver function during treatment.
  • Though rare, the use of Xermelo in combination with other medications that increase serotonin levels (such as antidepressants) may increase the risk of serotonin syndrome, a potentially life-threatening condition.
  • There is limited information on the safety of Xermelo during pregnancy or breastfeeding. Consult your healthcare provider before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Avoid Xermelo (Telotristat) If

  • If you have a known allergy to telotristat or any of the ingredients in Xermelo, you should not take this medication.
  • If you have severe liver problems, Xermelo may not be recommended, as it can affect liver function. Your healthcare provider will assess your liver function before prescribing Xermelo.
  • If you are pregnant or breastfeeding, discuss the potential risks with your healthcare provider before starting Xermelo.


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