Aloxi injection (Palonosetron)

Information about ALOXI Injection (Palonosetron)

ALOXI Injection, containing Palonosetron, is primarily used to prevent nausea and vomiting induced by chemotherapy treatments. 

ALOXI is used in children 1 month old to less than 17 years of age, with certain anti-cancer medicines (chemotherapy).

Product Highlights

• Effective in preventing acute and delayed nausea and vomiting associated with chemotherapy.
• Administered via injection, ensuring rapid onset of action and reliable absorption.

Key Ingredients

• Palonosetron hydrochloride
• Mannitol
• Disodium edetate and citrate buffer in water

Key Benefits

• Provides significant relief from chemotherapy-induced nausea and vomiting.
• Longer duration of action compared to other antiemetics, reducing the need for additional medication.
• Well-tolerated with minimal side effects.

Direction For Use

• ALOXI Injection is typically administered intravenously, either as a single dose before chemotherapy or as directed by a healthcare provider. 
• The dosage may vary depending on individual patient factors and the specific chemotherapy regimen.

DOSAGE AND ADMINISTRATION

Safety Concern

• Seek immediate medical attention if signs of an allergic reaction (e.g., rash, itching, and swelling) occur.
• Palonosetron may prolong QT interval in some patients; caution is advised in individuals with cardiac conditions or those taking medications affecting heart rhythm.
• Other common side effects include headache, constipation, and fatigue.

Avoid Taking ALOXI Injection if you:

• Are allergic to palonosetron or any ingredients in the formulation.
• Have a history of severe reactions to other serotonin 5-HT3 receptor antagonists.
• Are pregnant or breastfeeding without medical advice, as the safety of palonosetron in these conditions has not been fully established.