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Manufacturer for all European Galafold
Almac Pharma Services (Ireland) Limited
Finnabair Industrial Estate
Dundalk, Co. Louth
A91 P9KD
Ireland
Information about Galafold (Migalastat)
Galafold, also known as Migalastat, is an oral medication used for the treatment of Fabry disease, a rare genetic disorder that affects the body’s ability to break down certain fats, leading to a buildup that can cause various health problems.
Product Highlights
- Galafold is primarily indicated for the treatment of adults and adolescents (aged 16 and older) with Fabry disease who have specific genetic mutations that allow the drug to effectively reduce substrate accumulation.
Key Ingredient
Key Benefits
- Helps to restore enzyme activity and reduce globotriaosylceramide (Gb3) accumulation in various tissues.
- Aims to alleviate symptoms associated with Fabry disease, such as pain, renal impairment, and cardiovascular issues.
- Offers an alternative to enzyme replacement therapy, which typically requires intravenous administration.
Direction of Use
- Patients are advised to take Galafold as prescribed, usually 123 mg every other day.
- It can be taken with or without food, but consistency in how it is taken is important for optimal absorption.
Safety Concerns
- Frequently reported side effects may include headaches, nausea, diarrhea, and abdominal discomfort.
- Patients should be monitored for potential allergic reactions or changes in renal function.
- Periodic assessments of kidney function and other relevant biomarkers are recommended.
Avoid Galafold (Migalastat) If
- You have a known hypersensitivity to Migalastat or any of its components.
- You have severe renal impairment or end-stage renal disease, as the medication may not be effective in these cases.
- You are pregnant, considering pregnancy, or breastfeeding without first consulting a healthcare provider.
