Adcirca (Tadalafil)

Brand Options

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Brand Name : Adcirca

Marketing Authorization Holder : Eli Lilly

Prescription Required


Generic Option

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Generic Name : Tadalafil

Manufactured By : Authorized UK Generic

Prescription Required


Product Details


Information About Adcirca (Tadalafil)

Adcirca (tadalafil) is a medication primarily used to treat pulmonary Arterial hypertension (PAH) in lungs by improving exercise capacity and reducing symptoms.

The studies assessing the effectiveness of the medication predominantly involved patients who had pulmonary arterial hypertension (PAH) with New York Heart Association (NYHA) Functional Class II – III symptoms. The most of PAH cases (61%) were idiopathic or heritable, while 23% were linked to connective tissue disorders.

Product Highlights

  • Adcirca is primarily used for the treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and symptoms.
  • It relax the blood vessels in the lungs, which flow the blood easily.
  • Recommended dose is 40 mg once daily. It can be taken with or without food, before take medicine discuss with your doctor.
  • No dose adjustment is necessary for patients over 65 years old without renal or hepatic impairment.
  • Adcirca can interact with certain medications, particularly those that affect the metabolism of tadalafil through CYP3A4 inhibitors or inducers.

Direction of Use

  • The recommended dose of ADCIRCA is 40 mg, which is two 20 mg tablets taken once daily. It can be taken with or without food. It is advised not to divide the dose of 40 mg over the course of the day.

Key Benefits

  • ADCIRCA helps improve exercise ability in patients with pulmonary arterial hypertension (PAH), allowing them to engage in physical activities more comfortably.
  • It helps alleviate symptoms such as shortness of breath, fatigue, and dizziness associated with pulmonary arterial hypertension.
  • ADCIRCA has a long duration of action, providing sustained improvement in pulmonary arterial hypertension symptoms after oral administration.
  • It is administered once daily, making it convenient for patients to adhere to their treatment regimen.
  • Generally well-tolerated by patients, with common side effects being mild to moderate and manageable.

Key Ingredient

  • Tadalafil

Safety Concern

  • Read the label carefully before use.
  • Do not exceed the recommended dose.
  • It is unknown if ADCIRCA is safe and effective for use with younger patients.

Avoid Taking Adcirca If:

  • Take any medicines called nitrates.
  • Taking recreational substances known as "poppers," such as nitrite, amyl nitrate, or butyl nitrate.
  • Consume any guanylate cyclase stimulator-containing medications.
  • If you are allergic to tadalafil or any other ingredient in ADCIRCA.
  • Patients with pericardial constriction
  • Patients with restrictive or congestive cardiomyopathy
  • Patients with significant left ventricular dysfunction
  • Patients with life-threatening arrhythmias
  • Patients with symptomatic coronary artery disease
  • Patients with hypotension (<90/50 mm Hg) or uncontrolled hypertension

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