Each prefilled syringe contains 150 mg sarilumab in 1.14 ml solution (131.6 mg/ml).
Each prefilled syringe contains 200 mg sarilumab in 1.14 ml solution (175 mg/ml).
The UK medicines are the same dose as the US medicines. The difference is simply in the labeling requirement for the UK product.
Kevzara (sarilumab) is taken by adults on its own or in combination with methotrexate for the treatment of moderate to severe rheumatoid arthritis. Kevzara is used by patients who have not responded adequately (or are intolerant) to conventional medicines for rheumatoid arthritis.
Information about Kevzara (Sarilumab)
Kevzara (sarilumab) is a monoclonal antibody that inhibits the interleukin-6 (IL-6) receptor. It is used primarily in the treatment of moderate to severe rheumatoid arthritis in adults.
Product Highlights
The treatment of adults with moderate to severe rheumatoid arthritis who have had an inadequate response to one or more disease-modifying antirheumatic drugs (DMARDs).
Key Ingredient
Key Benefits
- Helps decrease inflammation and joint damage associated with rheumatoid arthritis.
- Can enhance physical function and quality of life for patients with rheumatoid arthritis.
- Subcutaneous injections can be self-administered, providing flexibility for patients.
Direction of Use
- The recommended starting dose is typically 200 mg administered subcutaneously every two weeks, with adjustments based on clinical response and tolerability.
- Inject into the thigh or abdomen; rotate injection sites to minimize discomfort.
- It is recommended to regularly monitor liver function tests and blood counts during treatment.
Safety Concerns
- Can increase the risk of serious infections, including tuberculosis.
- Potential for liver function abnormalities; requires monitoring.
- Rarely, may increase the risk of gastrointestinal perforations.
Avoid Kevzara (Sarilumab) If
- History of allergic reactions to sarilumab or any of its components.
- Presence of active infections, including tuberculosis or other serious infections.
- Avoid use in patients with severe liver disease or significant liver dysfunction.
This product requires special packaging to maintain its integrity during the shipping process. DO NOT USE THIS MEDICATION if the attached temperature indicator shows that the medication was exposed to temperatures below 2 degrees or above 8 degrees Celsius, and contact the pharmacy immediately.
