Kineret is an immunosuppressant containing anakinra, Anakinra is classified as a a cytokine, which blocks interleukin 1, a protein responsible for inflammation.
Kineret is used to treat rheumatoid arthritis along with other inflammatory diseases and conditions.
Information about Kineret (Anakinra)
Kineret is a biologic medication that contains anakinra, a recombinant form of the human interleukin-1 receptor antagonist (IL-1Ra). It is used primarily to reduce inflammation in various autoimmune and inflammatory conditions.
Product Highlights
- Used in adult patients, often in combination with other disease-modifying antirheumatic drugs (DMARDs).
- Treatment of patients with familial cold autoinflammatory syndrome (FCAS) and Muckle-Wells syndrome.
- Approved for treating systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still's disease.
Key Ingredient
Key Benefits
- Effectively lowers levels of inflammatory markers.
- Alleviates pain, stiffness, and other symptoms associated with rheumatoid arthritis and other inflammatory diseases.
- Generally has a favorable safety profile compared to some other biologics.
Direction of Use
- Initial dosing typically involves a loading dose (e.g., 100 mg/day) for rheumatoid arthritis, followed by a maintenance dose. For CAPS and Still's disease, doses may vary based on the patient's weight and clinical response.
- Given as a subcutaneous injection; patients should be trained on proper injection techniques.
Safety Concerns
- Increased risk of serious infections due to immune modulation.
- Possible local reactions such as redness, swelling, or pain at the injection site.
- Regular monitoring for signs of infections and blood cell counts is advised during treatment.
Avoid Kineret (Anakinra) If
- Patients with a known hypersensitivity to anakinra or any component of the formulation.
- Those with active infections should not receive Kineret.
- Caution is advised in patients with severe kidney dysfunction; dosage adjustments may be necessary.
- Limited data; caution is advised if considering use during pregnancy or breastfeeding.
This product requires special packaging to maintain its integrity during the shipping process. DO NOT USE THIS MEDICATION if the attached temperature indicator shows that the medication was exposed to temperatures below 2 degrees or above 8 degrees Celsius, and contact the pharmacy immediately.
