Vimovo (Naproxen / Esomeprazole)

Vimovo is a combination drug containing naproxen and esomeprazole.  The combination of a NSAID (non-steroidal anti-inflammatory) for pain and inflammation along with a PPI (proton pump inhibitor) for reduction of stomach acid works well to provide relief alongside of ulcer protection.

Vimovo is prescribed for symptomatic relief of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.  Vimovo reduces swelling, pain, redness and inflammation.

Information about Vimovo (Naproxen / Esomeprazole)

Vimovo is a combination medication that contains Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), and Esomeprazole, a proton pump inhibitor (PPI). This combination is designed to treat conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis while minimizing the risk of gastrointestinal side effects associated with NSAIDs. Esomeprazole helps reduce the risk of stomach ulcers or gastrointestinal bleeding that can occur with prolonged use of Naproxen.

Product Highlights

• To reduce pain, inflammation, and stiffness in the joints.
• To alleviate symptoms like joint pain, swelling, and stiffness. 
• To help manage pain and inflammation in the spine and other joints.
• For short-term pain relief in conditions like musculoskeletal pain, gout, or certain forms of mild-to-moderate pain.
• Key Ingredient

Naproxen

• Esomeprazole

Key Benefits

• Naproxen effectively reduces inflammation, pain, and stiffness associated with conditions like osteoarthritis and rheumatoid arthritis.
• Esomeprazole helps protect the stomach from damage caused by NSAIDs, reducing the risk of ulcers and bleeding.
• The combination of both medications in a single tablet makes it easier for patients to manage their condition without having to take separate medications for pain relief and stomach protection.
• Naproxen has a prolonged action, providing long-term relief from pain and inflammation, which may reduce the need for frequent dosing.

Direction of Use

• Vimovo is usually taken once or twice daily, depending on the prescribed dose. The typical dose is 1 tablet (500 mg Naproxen / 20 mg Esomeprazole) once or twice daily.
• It is recommended to take Vimovo with food to help reduce stomach irritation and improve the absorption of Esomeprazole.
• Do not crush, chew, or split the tablet.
• Take the medication at the same time each day to help maintain steady blood levels of the drug.

Safety Concerns

• While Esomeprazole helps protect the stomach, Naproxen can still cause stomach irritation, ulcers, and bleeding, especially with long-term use. Monitoring for symptoms of gastrointestinal bleeding, such as black or bloody stools, is important.
• NSAIDs like Naproxen can increase the risk of heart attack, stroke, and high blood pressure. It is important to use Vimovo at the lowest effective dose for the shortest duration.
• Prolonged use of Naproxen can impair kidney function, particularly in individuals with pre-existing kidney conditions. Kidney function should be monitored during long-term use.
• Esomeprazole and Naproxen can impact liver enzymes. Liver function should be monitored during treatment, especially for patients with existing liver conditions.
• Both Naproxen and Esomeprazole can cause allergic reactions. Symptoms may include skin rash, swelling, difficulty breathing, or chest pain. Immediate medical help should be sought if any severe allergic reactions occur.

Avoid Vimovo (Naproxen / Esomeprazole) If

• You have a known allergy to Naproxen, Esomeprazole, or any of the ingredients in Vimovo.
• You have a history of gastrointestinal ulcers, bleeding, or perforation, particularly those caused by NSAIDs.
• You have severe liver disease or kidney disease.
• You have heart disease, especially if you have a history of heart attack or stroke.
• You are currently taking other NSAIDs, blood thinners, or have a history of stomach bleeding.
• You are pregnant (particularly during the third trimester) or are breastfeeding, as Vimovo may not be safe during these times.
• You have a history of severe allergic reactions to NSAIDs, PPIs, or related medications.