Coartem (Riamet in UK) is an antimalarial combination containing artemether and lumefantrine. Coartem is used in both adults and children.
Coartem treats acute uncomplicated malaria caused by Plasmodium falciparum, a single celled parasite. It is not meant for prevention of malaria or the treatment severe cases of malaria.
Information about Coartem (Artemether / Lumefantrine)
Coartem is a combination medication used to treat malaria. It contains two active ingredients: artemether and lumefantrine. Artemether is a fast-acting antimalarial, while lumefantrine has a longer duration of action, helping to clear the parasite from the bloodstream and prevent relapse.
Product Highlights
Treatment of uncomplicated malaria caused by Plasmodium falciparum, the most severe form of malaria, particularly in areas where the parasite is resistant to other antimalarial drugs.
Key Ingredient
Artemether
Lumefantrine
Key Benefits
Artemether provides rapid relief by quickly reducing the number of malaria parasites in the bloodstream.
Lumefantrine ensures prolonged action, reducing the risk of relapse and preventing the development of drug resistance.
The combination of artemether and lumefantrine offers a synergistic effect, improving overall efficacy against malaria.
Direction of Use
The usual dose is 4 tablets taken twice daily for 3 days. Dosage may vary based on patient weight, age, and local guidelines.
Tablets per dose by bodyweight; total of 6 doses over 3 days
5 to < 15 kg
1 Tablet
15 to < 25 kg
2 Tablet
25 to < 35 kg
3 Tablet
35 kg and over
4 Tablet
Tablets should be taken with food or a fatty meal to enhance absorption.
Follow the prescribed schedule strictly to ensure complete eradication of the parasite and minimize the risk of relapse.
Safety Concerns
May include nausea, vomiting, headache, dizziness, abdominal pain, and diarrhea.
Rare but serious side effects include allergic reactions, severe skin reactions, or liver dysfunction. Patients should be monitored for any signs of severe adverse effects.
Coartem may interact with other medications, including some antiepileptics and drugs affecting liver enzymes. It is important to notify healthcare providers of all medications being used.
Avoid Coartem (Artemether / Lumefantrine) If
Avoid use in patients with known hypersensitivity or allergy to artemether, lumefantrine, or any other component of the medication.
Caution is advised in patients with severe liver impairment, as this can affect drug metabolism and increase the risk of adverse effects.
Although Coartem is generally considered safe during pregnancy, especially in the second and third trimesters, it should be used only if clearly needed and under medical supervision. In the first trimester, use should be limited to situations where no safer alternatives are available.
