Duopa intestinal gel is called Duodopa in Europe.
Duopa intestinal gel, called Duodopa in the UK, is used to treat advanced Parkinson's disease which is responsive to levodopa therapy as a secondary therapy when other medicines do not give satisfactory results.
Duopa gel is administered continuously. Long-term administration requires that Duopa should be administered with a portable pump into the duodenum or upper jejunum permanently via tube. Administration is as per your doctors requirement.
Duopa should be as a monotherapy (alone) when used initially. Additional medicine may be added as per your physician.
Each medicine cassette is for single use only for not more than 16 hours. Opened cassettes are not to be used again.
Information about Duopa Intestinal Gel
Duopa is a medication that combines carbidopa and levodopa delivered as a continuous intestinal gel. It is designed for the treatment of advanced Parkinson's disease, providing stable levodopa levels and improving motor function while minimizing "off" periods.
Product Highlights
- Indicated for patients with advanced stages of Parkinson's who experience motor fluctuations not adequately controlled by oral medications.
- Helps reduce fluctuations in motor symptoms associated with Parkinson's disease.
Key Ingredient
Key Benefits
- Maintains stable levodopa levels, minimizing "off" periods and enhancing overall motor function.
- Helps patients achieve better control over their symptoms, allowing for improved daily functioning.
- Provides a method for continuous delivery, which can lead to more effective symptom management.
Direction of Use
- Delivered via a specialized infusion pump directly into the small intestine.
- Follow the prescribing physician's instructions for dosage adjustments and administration timing.
Safety Concerns
- May include nausea, vomiting, abdominal pain, and dyskinesia (involuntary movements).
- Potential for psychiatric symptoms, including hallucinations; monitor for any significant mood changes.
- Risk of complications such as aspiration pneumonia and gastrointestinal obstruction.
Avoid Duopa Intestinal Gel If
- If you have a known hypersensitivity to carbidopa, levodopa, or any component of the formulation.
- Should not be used in patients with this condition due to potential increases in intraocular pressure.
- Use is contraindicated in patients with severe hepatic or renal impairment.
This product requires special packaging to maintain its integrity during the shipping process. DO NOT USE THIS MEDICATION if the attached temperature indicator shows that the medication was exposed to temperatures below 2 degrees or above 8 degrees Celsius, and contact the pharmacy immediately.
