Solian (Amisulpride)

Brand Options

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Brand Name : Solian

Marketing Authorization Holder : SANOFI

Prescription Required

 
 

Generic Option

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Generic Name : Amisulpride

Manufactured By : Authorized UK Generic

Prescription Required

 
 

Product Details

Solian

Solian is used to treat schizophrenia, which causes a person to feel, hear, or see things that are not real, give frightening or strange thoughts, cause strange behavior or make a person feel lonely.  Often depresssion, anxiety and tension are also symptoms of schizophrenia.  Solian improves these symptoms and is often a long term treatment option.

Solian can be given once per day up to 300mg and higher doses of Solian should be split into two doses per day.  Always the minimum effective dose of Solian is administered.

Information about Solian (Amisulpride)

Solian is a medication that contains amisulpride as its active ingredient. It is an atypical antipsychotic primarily used to treat symptoms of schizophrenia and other psychiatric disorders. Amisulpride works by regulating dopamine receptors in the brain, helping to control mood, thoughts, and behavior in individuals with psychiatric conditions. Solian is commonly prescribed to treat both positive symptoms (such as hallucinations or delusions) and negative symptoms (such as low motivation or social withdrawal) of schizophrenia.

Product Highlights

  • Solian is mainly used for the treatment of schizophrenia in adults, particularly to help reduce the severity of both positive (e.g., hallucinations, delusions) and negative symptoms (e.g., emotional blunting, social withdrawal).
  • It may also be used off-label for other conditions such as depression or anxiety, particularly when conventional antidepressants are ineffective.

Key Ingredient

  • Amisulpride

Key Benefits

  • Amisulpride is effective in treating both the positive and negative symptoms of schizophrenia, helping patients regain normal social and cognitive functions.
  • Compared to older antipsychotics, amisulpride tends to have fewer sedative and motor-related side effects, making it a preferred choice in some patients.
  • It may provide prolonged symptom control with consistent dosing, typically once or twice a day.
  • The risk of movement-related side effects (such as tremors and rigidity) is lower than with many older antipsychotics.

Direction of Use

  • Solian is typically taken in tablet form. The usual starting dose for adults with schizophrenia ranges from 400 mg to 800 mg daily, depending on the severity of the symptoms. The dose may be adjusted based on the individual’s response and tolerance.
  • The tablets should be taken with or without food, and it is important to follow the dosage instructions provided by the healthcare provider.
  • To ensure the best results, take the medication consistently at the same times each day.

Safety Concerns

  • Common side effects of amisulpride may include dizziness, drowsiness, headache, weight gain, and gastrointestinal issues like nausea or constipation. More severe side effects, though less common, can include heart rhythm problems (QT prolongation) and movement disorders.
  • Like many antipsychotics, amisulpride may cause weight gain, changes in cholesterol levels, and an increased risk of diabetes. It is recommended to regularly monitor weight, blood sugar, and lipid levels. 
  • Some individuals may experience sedation, especially when starting the medication, which could impair driving or operating machinery.
  • In rare cases, amisulpride can cause changes in heart rhythm (QT interval prolongation), so caution is advised in individuals with heart conditions.

Avoid Solian (Amisulpride) If

  • If you are allergic to amisulpride or any of the ingredients in Solian, you should not use it. 
  • Solian should not be used if you have a history of certain heart conditions, including arrhythmias or prolonged QT syndrome, as it may worsen these conditions.
  • Solian is contraindicated in patients with severe renal (kidney) impairment as it is primarily excreted through the kidneys.
  • Solian is not recommended during pregnancy, particularly in the first trimester, due to potential risks to the developing fetus. It is also not recommended while breastfeeding, as it may be passed into breast milk. 
  • Solian is generally not recommended for use in children or adolescents under 18, unless specifically directed by a healthcare provider.
  • Combining Solian with other antipsychotics may increase the risk of severe side effects, including movement disorders and sedation, and should be done only under strict medical supervision.


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