Antabuse (Disulfiram)

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Generic Name : Disulfiram

Manufactured By : Authorized Indian Generic

Prescription Required

 
 

Product Details

Antabuse

Information about Antabuse (Disulfiram)

Antabuse, also known by its generic name Disulfiram, is primarily used to support the treatment of chronic alcoholism. By interfering with the metabolism of alcohol in the body, causing unpleasant reactions when alcohol is consumed. 

This deterrent effect helps individuals stay away from alcohol as part of a comprehensive treatment program for alcohol dependence. Disulfiram is a compound that works by blocking the breakdown of acetaldehyde, a byproduct of alcohol metabolism.

Product Highlights

  • Antabuse is available in oral tablet form.
  • Disulfiram inhibits the enzyme acetaldehyde dehydrogenase, which is involved in breaking down alcohol in the liver. This leads to the accumulation of acetaldehyde, causing unpleasant symptoms when alcohol is consumed.

Key Ingredients

  • Disulfirum

Key Benefits

  • By inducing adverse reactions when alcohol is consumed, Antabuse helps discourage drinking.
  • Used as part of a broader treatment plan including counseling and support groups, it aids in long-term abstinence from alcohol.
  • The discomfort caused by alcohol ingestion when on Antabuse reinforces the motivation to avoid alcohol.

Direction For Use

  • Four 200 mg tablets (800 mg) daily for 2 to 3 days, but it can be adjusted based on the individual’s response and tolerability.
  • Take the tablet orally with water, usually after a meal to reduce gastrointestinal upset.
  • It’s important to follow the prescribed dosage and schedule strictly. Regular follow-up with a healthcare provider is necessary to monitor progress and adjust the treatment if needed.

Safety Concern

  • If alcohol is consumed while taking Antabuse, it can cause severe reactions including flushing, nausea, vomiting, palpitations, and sweating. This can be distressing and potentially dangerous.
  • Use with caution in patients with liver disease or other medical conditions. Liver function should be monitored regularly.
  • Disulfiram can interact with certain medications and substances, so it's important to inform your healthcare provider of all other drugs and supplements you are taking.
  • Possible side effects include drowsiness, fatigue, headache, and rash. Serious reactions, although rare, should be reported to a healthcare provider immediately.

When to Avoid Antabuse (Disulfiram)

  • Do not use if you are allergic to disulfiram or any of its components.
  • Do not start Antabuse if you are currently drinking alcohol or if you have consumed alcohol recently, as this can trigger severe reactions.
  • Avoid if you have severe liver disease, as disulfiram can exacerbate liver problems.
  • Avoid use if you are taking certain medications that may interact adversely with disulfiram. Always discuss with your healthcare provider before starting treatment.

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