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Information about Nexletol (bempedoic acid)
Nexletol (Bempedoic Acid) is a medication used primarily to help lower cholesterol levels, specifically in patients who are at risk of cardiovascular disease and who have not been able to achieve adequate cholesterol reduction with statins or other treatments. It is typically prescribed alongside a statin or other lipid-lowering therapies to further help control cholesterol levels.
Product Highlights
- To help lower LDL cholesterol levels in patients with primary hyperlipidemia (high cholesterol).
- In individuals with this genetic condition causing elevated cholesterol.
- Typically used with a statin or other lipid-lowering medications for better cholesterol control in high-risk cardiovascular patients.
Key Ingredient
Key Benefits
- Helps lower "bad" cholesterol (LDL), which is a major contributor to cardiovascular disease risk.
- In combination with other treatments, it can reduce the risk of heart attacks and strokes in high-risk individuals.
- For patients who cannot tolerate statins, Nexletol offers a viable alternative to help manage cholesterol levels.
- Nexletol is usually taken once daily, making it easy for patients to incorporate into their routine.
Direction of Use
- Nexletol is taken once daily, typically in the form of a tablet.
- It can be taken with or without food, based on patient preference.
- It is often prescribed in combination with a statin or ezetimibe (another cholesterol-lowering medication) to maximize the reduction of LDL cholesterol.
Safety Concerns
- Bempedoic acid may increase the risk of gout due to increased uric acid levels. Patients with a history of gout should be closely monitored.
- Bempedoic acid can cause elevations in liver enzymes, so regular liver function tests are recommended during treatment.
- Though bempedoic acid is generally well-tolerated, it can cause muscle-related side effects like pain or weakness, though less commonly than statins.
- Not recommended for use during pregnancy or while breastfeeding due to limited safety data.
- May interact with certain drugs, including those that affect liver enzymes, so it's important to disclose all medications to your doctor.
Avoid Nexletol (Bempedoic Acid) If
- There is insufficient data regarding its safety during pregnancy and lactation, so it should be avoided.
- Patients with severe liver disease should not use Nexletol due to the risk of liver-related side effects.
- Because bempedoic acid may raise uric acid levels, it should be used cautiously or avoided in patients with a history of gout.
- Any patient with a known hypersensitivity or allergy to bempedoic acid or any of the ingredients in the product should avoid its use.
