Information about Wellbutrin ER (Bupropion)
Wellbutrin ER (extended-release) is a prescription medication that contains bupropion, a type of antidepressant. It is primarily used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD), as well as to aid in smoking cessation. Bupropion works by influencing the neurotransmitters in the brain, particularly dopamine and norepinephrine, to help improve mood, decrease cravings, and manage withdrawal symptoms.
Product Highlights
- To help improve mood and reduce symptoms of depression in adults.
- A type of depression that occurs seasonally, often during the winter months when there is less sunlight.
- As part of a smoking cessation program to help individuals quit smoking by reducing cravings and withdrawal symptoms.
- Wellbutrin is also sometimes used off-label for attention deficit hyperactivity disorder (ADHD) or to manage anxiety.
Key Ingredient
Key Benefits
- Wellbutrin ER helps improve mood, energy levels, and overall well-being in patients with depression.
- It reduces cravings and withdrawal symptoms for individuals trying to quit smoking.
- Unlike many other antidepressants, Wellbutrin has a lower risk of sexual side effects, such as decreased libido or erectile dysfunction.
- Wellbutrin is less likely to cause weight gain compared to other antidepressants, and some patients may even lose a small amount of weight.
- The extended-release formulation allows for once-daily dosing, making it easier for patients to adhere to the treatment regimen.
Direction of Use
- Wellbutrin ER is typically started at a lower dose, often 150 mg once daily, and can be increased to 400 mg per day based on individual needs and tolerability. Your healthcare provider will decide the correct dosage based on your individual condition.
- Take the tablet whole, without chewing, splitting, or crushing, to prevent overdose and ensure proper absorption.
- It should be taken once a day, preferably in the morning to avoid potential interference with sleep.
- It is important to take Wellbutrin ER regularly and at the same time each day to maintain steady levels in your body.
Safety Concerns
- One of the most serious risks associated with Wellbutrin is an increased risk of seizures, especially in individuals with certain risk factors, such as eating disorders, alcohol or drug withdrawal, or a history of seizures.
- Wellbutrin can cause mood swings, agitation, or increased risk of suicidal thoughts, especially in young adults. Close monitoring is necessary, particularly during the first few weeks of treatment.
- Wellbutrin may cause insomnia or difficulty sleeping, especially if taken late in the day. It’s recommended to take the medication in the morning.
- Wellbutrin can cause an increase in blood pressure, so regular monitoring of blood pressure is advised, particularly in patients with hypertension.
- Bupropion can interact with other medications, including monoamine oxidase inhibitors (MAOIs), other antidepressants, and drugs that increase the risk of seizures.
Avoid Wellbutrin ER (Bupropion) If
- You have a seizure disorder or are at increased risk for seizures (e.g., due to alcohol or drug withdrawal, eating disorders, or head trauma).
- You are taking monoamine oxidase inhibitors (MAOIs) or have recently stopped taking them (within 14 days), as combining these medications can lead to serious, potentially life-threatening interactions.
- You have a history of eating disorders (such as bulimia or anorexia), as these conditions increase the risk of seizures with Wellbutrin.
- You are pregnant or planning to become pregnant, as Wellbutrin may not be safe during pregnancy. Speak with your healthcare provider about the possible risks and benefits.
- You are breastfeeding, as bupropion may pass into breast milk and affect the infant.
- You have severe liver disease or kidney impairment, as Wellbutrin may need to be adjusted or avoided depending on the severity of these conditions.
