Brand Name : Creon
Marketing Authorization Holder : AbbVie
℞ Prescription Required
Generic Name : enzymes
Manufactured By : Authorized Indian Generic
℞ Prescription Required
Creon 10 (also called Creon 10,000)
Lipase | 10,000 PhEur units (=10,000 USP units) |
Amylase | 8,000 PhEur units (= 33,200 USP units) |
Protease | 600 PhEur units (= 37,500 USP units) |
Creon 25:
Lipase | 25,000 PhEur units ( = 25,000 USP units) |
Amylase | 18,000 PhEur units (= 74,700 USP units) |
Protease | 1,000 PhEur units (= 62,500 USP units) |
Creon 40: Lipase 40,000 - Amylase 103,750 USP (25,000 EU) - Protease 100,000 USP (1600 EU)
Here are the US version of Creon:
CREON is available in US most commonly in capsule strengths of:
● 6,000 USP units of lipase; 19,000 USP units of protease; 30,000 USP units of amylase
● 12,000 USP units of lipase; 38,000 USP units of protease; 60,000 USP units of amylase
● 24,000 USP units of lipase; 76,000 USP units of protease; 120,000 USP units of amylase
They also have: 36,000 USP units of lipase, 114000 units of protease, 180,000 USP units of amylase
Creon is a prescription medication that contains pancreatin, a mixture of digestive enzymes including amylase, lipase, and protease. It is used to aid digestion in individuals whose pancreas does not produce enough enzymes naturally. By supplementing these essential enzymes, Creon helps improve digestion and nutrient absorption.
Weight Based Dosing Recommendations for the Treatment of Paediatric and Adult Patients with Cystic Fibrosis (CF) using Creon
Patient Age | Starting Dose | Titration Considerations | Maximum Dose |
Children < 4 years | 1,000 units lipase/kg bodyweight per meal | Adjust dose according to: • disease severity • control of steatorrhoea • maintenance of good nutritional status | 4,000 units lipase/g dietary fat intake OR 10,000 units lipase/kg bodyweight per day |
Patients ≥ 4 years | 500 units lipase/kg bodyweight per meal |
Dosing Recommendations in Adult Patients using Creon for the Treatment of Pancreatic Exocrine Insufficiency (PEI) Associated with other Conditions
Starting Dose | Titration Considerations | If required, increase to: | |
Meal | 25,000 to 40,000 units lipase | Assess patient for clinical response and compliance to therapy. | 80,000 units lipase |
Snack | Half of meal dose | Half of meal dose |