We ship Adcetris manufactured in Austria by cold chain shipping from our pharmacy in India.
Information About ADCETRIS
ADCETRIS treats Hodgkin lymphoma, systemic anaplastic large cell lymphoma, primary cutaneous anaplastic large cell lymphoma, and CD30-expressing mycosis fungoides.
It targets tumor cells expressing the CD30 antigen, which is characteristic of Hodgkin lymphoma and ALCL.
Product Highlights
ADCETRIS (brentuximab vedotin) consists of 3 main components:
The chimeric IgG1 antibody cAC10, targeting human CD30.
The microtubule disrupting agent MMAE.
A protease-cleavable linker that attaches MMAE to cAC10 covalently.
ADCETRIS (brentuximab vedotin) is use for the treatment of in adult patients with CD30+ cutaneous T-cell lymphoma (CTCL) who have done at least 1 prior systemic therapy.
Key Ingredients
Trehalose dihydrate
Sodium citrate dihydrate
Citric acid monohydrate
Polysorbate 80
Water for injection
Key Benefits
The benefits of ADCETRIS (brentuximab vedotin) include targeted therapy against CD30-expressing cancers like Hodgkin lymphoma and systemic anaplastic large cell lymphoma, potentially leading to more effective treatment outcomes with reduced impact on healthy cells.
Direction For Use
Sample calculations for patients receiving the recommended dose of 1.8 mg/kg of ADCETRIS for weights ranging from 60 kg to 120 kg.
Patient weight (kg)
Total dose = patient weight multiplied by recommended dose [1.8 m g/kga ])
Total volume to be dilutedb = total dose divided by reconstituted vial concentration [5 mg/mL])
Number of vials needed = total volume to be diluted divided by total volume per vial [10 mL/vial])
60 kg
108 mg
21.6 mL
2.16 vials
80 kg
144 mg
28.8 mL
2.88 vials
100 kg
180 mg
36 mL
3.6 vials
120 kg c
18 mg d
36 mL
3.6 vials
Sample calculations for patients receiving the recommended dose of 1.2 mg/kg of ADCETRIS for weights ranging from 60 kg to 120 kg when a reduced dose is required.
Patient weight (kg)
Total dose = patient weight multiplied by recommended dose [1.2 mg/kg])
Total volume to be diluteda = total dose divided by reconstituted vial concentration [5 mg/mL])
Total volume to be diluteda = total dose divided by reconstituted vial concentration [5 mg/mL])
60 kg
72 mg
14.4 mL
1.44 vials
80 kg
96 mg
19.2 mL
1.92 vials
100 kg
120 mg
24 mL
2.4 vials
120 kg b
120 mg
24 mL
2.4 vials
Safety Concern
Read the label carefully before use.
Do not exceed the recommended dose.
ADCETRIS (brentuximab vedotin) may include potential side effects such as infusion reactions, peripheral neuropathy, and risk of infections.
How to Take
For ADCETRIS (brentuximab vedotin), follow the directions provided by your healthcare provider regarding administration and dosage.
Avoid Taking ADCETRIS If:
You have an allergy to ADCETRIS
The packaging is torn or has signs of tampering.
The medicine has expired as it may not work if taken after the expiry date.
This product requires special packaging to maintain its integrity during the shipping process. DO NOT USE THIS MEDICATION if the attached temperature indicator shows that the medication was exposed to temperatures below 2 degrees or above 8 degrees Celsius, and contact the pharmacy immediately.
The product may appear different from the product illustrated here
