Information about Pristiq (desvenlafaxine ER)
Pristiq (desvenlafaxine ER) is a prescription medication primarily used to treat major depressive disorder (MDD) and other mood-related conditions. It is an extended-release formulation, designed to deliver a steady dose of the active ingredient throughout the day, and is a member of the serotonin-norepinephrine reuptake inhibitor (SNRI) class of antidepressants.
Product Highlights
- Primarily prescribed for the treatment of depression in adults, helping to improve mood and alleviate symptoms like fatigue, poor concentration, and feelings of hopelessness.
- Used to treat symptoms of anxiety, including excessive worry, restlessness, and tension.
- Sometimes prescribed off-label for conditions like chronic pain, fibromyalgia, or menopausal hot flashes, depending on the patient's specific needs and doctor's recommendation.
Key Ingredient
Key Benefits
- Pristiq helps alleviate symptoms of major depressive disorder, such as sadness, lack of interest, and sleep problems.
- In addition to treating depression, Pristiq is beneficial in managing anxiety symptoms.
- The extended-release formulation provides a consistent therapeutic effect with once-daily dosing, reducing the need for multiple doses throughout the day.
- Helps enhance overall mood, energy levels, and functioning in daily life by increasing the availability of key neurotransmitters.
Directions for Use
- The usual starting dose of Pristiq is 50 mg, taken once a day. Depending on the patient’s response, the dose may be adjusted to a maximum of 100 mg daily.
- Take the tablet once daily, with or without food. Swallow it whole—do not break, crush, or chew it.
- It's important to take the medication at the same time every day to maintain steady drug levels in your body.
Safety Concerns
- Common side effects of Pristiq include nausea, dizziness, dry mouth, fatigue, and increased sweating. In some cases, it may cause sexual side effects, insomnia, or appetite changes.
- Discontinuing Pristiq suddenly can lead to withdrawal symptoms such as dizziness, irritability, nausea, and electric shock-like sensations. It is advisable to slowly decrease the dose with the guidance of a healthcare provider.
- Serotonin syndrome is a rare, but potentially life-threatening condition resulting from an excess of serotonin in the brain. Symptoms may include agitation, confusion, rapid heartbeat, and muscle stiffness.
- Like other antidepressants, Pristiq carries a warning about an increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults.
Avoid Pristiq (Desvenlafaxine ER) If
- Avoid using this medication if you are allergic to desvenlafaxine or any of its ingredients.
- Do not take Pristiq if you are currently taking an MAOI or have recently stopped using one, as it may lead to serious interactions.
- Pristiq should be used with caution or avoided if you have severe liver or kidney problems, as it may worsen these conditions.
- Those with uncontrolled high blood pressure or heart conditions should avoid taking Pristiq unless directed by a healthcare provider.
- Pristiq should be used during pregnancy only if the benefits outweigh the potential risks. It is excreted in breast milk, so caution is needed if breastfeeding.