Buy Actoplus (Pioglitazone / Metformin) Online

Product Details

Actoplus

Actoplus brand medicine goes by the trade names Actoplus Met and Competact in Europe.

Information About Medicine ACTOPLUS MET

ACTOPLUS MET is a prescription medication that combines two diabetes drugs: pioglitazone and metformin. It is used to treatment of type 2 diabetes in adults.

Pioglitazone belongs to a class of drugs called thiazolidinediones, which help improve insulin sensitivity and reduce glucose production in the liver.

Metformin belongs to the biguanide class and works primarily by decreasing glucose production in the liver and improving insulin sensitivity in the muscles.

Key Benefits:

Helps control blood sugar levels by addressing insulin resistance and reducing glucose production in the liver.
Most of the time prescribed as part of a treatment plan that includes diet and exercise.

Common Side Effects of ACTOPLUS MET

Weight gain
Liver problems
Cold-like symptoms (upper respiratory infection)
Headache
Urinary tract infection
Dizziness
Sinus infection
Anemia

How To Take:

ACTOPLUS MET is a tablet for oral administration.

ACTOPLUS MET Dosage Recommendations

ACTOPLUS MET

Pioglitazone/immediate-release metformin hydrochloride

Tablet strengths

15 mg/500 mg 15 mg/850 mg

Starting Dose

15 mg/500 mg or 15 mg/850 mg tablets once or twice daily with food

Maximum Recommended Daily Dose

45 mg/2550 mg administered in divided doses with food

Mean (SD) Pharmacokinetic Parameters for ACTOPLUS

Regimen	N	AUC(0-inf) (ng. h/mL)	N	Cmax (ng/mL)	N	Tmax (h)	N	T1/2 (h)
Pioglitazone HCl
15 mg/500 mg ACTOPLUS MET	51	5984 (1599)	63	585 (198)	63	1.83 (0.93)	51	8.69 (3.86)
15 mg ACTOS and 500 mg Glucophage	54	5810 (1472)	63	608 (204)	63	1.75 (0.90)	54	7.90 (3.08)
15 mg/850 mg ACTOPLUS MET	52	5671 (1585)	60	569 (222)	60	1.89 (0.80)	52	7.19 (1.84)
15 mg ACTOS and 850 mg Glucophage	55	5957 (1680)	61	603 (239)	61	2.01 (1.54)	55	7.16 (1.85)
Metformin HCl
15 mg/500 mg ACTOPLUS MET	59	7783 (2266)	63	1203 (325)	63	2.32 (0.88)	59	8.57 (14.30)
15 mg ACTOS and 500 mg Glucophage	59	7599 (2385)	63	1215 (329)	63	2.53 (0.95)	59	6.73 (5.87)
15 mg/850 mg ACTOPLUS MET	47	11927 (3311)	60	1827 (536)	60	2.41 (0.91)	47	17.56 (20.08)
15 mg ACTOS and 850 mg Glucophage	52	11569 (3494)	61	1797 (525)	61	2.26 (0.85)	52	17.01 (18.09)

Safety Concern

Should not be used in patients with severe renal impairment, heart failure, or active bladder cancer.
Regular monitoring of blood sugar levels and kidney function is recommended during treatment.

Avoid taking Actoplus if:

You have an allergy to Actoplus.
The packaging is torn or has signs of tampering.
The medicine has expired. It may not work if taken after the expiry date.

The product may appear different from
the product illustrated here

Actoplus (Pioglitazone / Metformin)

Brand Options

Generic Option