Save 75% over US brand Vyndamax prices. Vyndamax is called Vyndamx by Pfizer in international markets.
Pfizer Manufacturing Site for this product:
Millmount Healthcare Limited
Block-7, City North Business Campus
Stamullen, Co. Meath
Ireland - K32 YD60
Information about Vyndamax (Tafamidis)
Vyndamax is an oral medication that contains tafamidis, a stabilizer of transthyretin. Tafamidis works by binding to and stabilizing the transthyretin (TTR) protein, which is crucial for transporting thyroid hormone and vitamin A in the blood. In conditions where TTR is misfolded or destabilized, it can form amyloid deposits in tissues, leading to transthyretin amyloidosis (ATTR), a potentially life-threatening disease. Vyndamax helps prevent this destabilization, thereby reducing amyloid buildup and improving overall patient outcomes in ATTR-related conditions.
Product Highlights
- Vyndamax is used to treat heart-related complications of ATTR, especially cardiomyopathy resulting from amyloid deposits in the heart.
- Vyndamax is also indicated for treating polyneuropathy caused by amyloid deposits affecting the peripheral nerves, leading to symptoms such as numbness, tingling, and pain in the extremities.
Key Ingredient
Key Benefits
- Tafamidis helps slow the progression of transthyretin amyloidosis, reducing symptoms and improving overall quality of life for patients with ATTR-CM and ATTR-PN.
- Vyndamax can reduce amyloid deposits in both the heart (for ATTR-CM) and nerves (for ATTR-PN), improving cardiac function and alleviating symptoms related to nerve damage.
- In clinical trials, tafamidis has demonstrated the potential to improve survival rates and delay the need for heart transplants in ATTR-CM patients.
- Vyndamax is taken orally, offering a convenient option compared to other treatments for amyloidosis that may require injections or infusions.
Direction of Use
- The recommended dose of Vyndamax is 61 mg, taken once daily.
- Vyndamax is typically taken with food, but it can be taken with or without food.
- For the best effect, Vyndamax should be taken once daily, at the same time each day. Consistency in administration is important for maintaining stable blood levels of the medication.
- Vyndamax is available in oral capsule form, which should be swallowed whole. Do not crush or chew the capsules.
Safety Concerns
- Patients taking Vyndamax should be monitored for liver function as the drug can have an effect on liver enzymes. Liver function tests should be performed regularly.
- Vyndamax is not recommended during pregnancy, as its potential to harm an unborn baby is not known. Women who are pregnant should discuss alternative treatment options with their healthcare provider. The safety of tafamidis during breastfeeding is also unknown, and caution is advised.
- Vyndamax can interact with other medications. Always inform your healthcare provider about all medications you're currently taking, including over-the-counter drugs and supplements.
- While generally well-tolerated, Vyndamax should be used with caution in patients with pre-existing kidney disorders. Kidney function should be monitored periodically.
- Some common side effects include diarrhea, nausea, and upper respiratory tract infections. These are typically mild but should be reported to your healthcare provider if they become bothersome or persistent.
Avoid Vyndamax (Tafamidis) If
- You are allergic to tafamidis or any of the other ingredients in Vyndamax.
- You have severe liver disease or liver dysfunction, as Vyndamax can impact liver function.
- You are pregnant, planning to become pregnant, or are breastfeeding, as the effects of tafamidis on pregnancy and lactation are not well established.
- You have a severe kidney condition that could be aggravated by the medication.
