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Information about Besivance (Besifloxacin)
Besivance is a topical antibiotic eye drop solution used for the treatment of bacterial conjunctivitis, commonly known as pink eye. It contains the active ingredient besifloxacin, which belongs to the class of drugs known as fluoroquinolones. Besifloxacin works by inhibiting bacterial DNA synthesis, thereby preventing bacterial growth and resolving infections in the eye.
Besifloxacin a broad-spectrum fluoroquinolone antibiotic specifically formulated for ocular infections. It has a high affinity for bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication.
Product Highlights:
- Use to treatment of bacterial conjunctivitis (pink eye).
- Available in form of eye drops.
- A potent fluoroquinolone specifically designed for ocular infections.
- Inhibits bacterial DNA gyrase and topoisomerase IV, crucial enzymes for bacterial DNA replication and repair.
Key Ingredient:
- Besifloxacin Hydrochloride
Key Benefits:
- Targets a wide range of bacteria that cause eye infections, including those resistant to other antibiotics.
- Directly applied to the eye, allowing for high concentrations at the site of infection with minimal systemic absorption.
- Typically administered three times a day for a short duration, which can enhance patient compliance.
- Limited systemic absorption reduces the risk of systemic side effects.
Direction of Use:
- Wash Hands: Always start by washing your hands to avoid contaminating the eye drops.
- Shake the Bottle: Gently shake the bottle before use.
- Instill Drops: Tilt your head back, pull down your lower eyelid, and place the prescribed number of drops into the lower conjunctival sac (the space between the lower eyelid and the eye). Avoid touching the dropper tip to the eye or any surface to keep it sterile.
- Close Eyes: Close your eyes gently and press lightly on the inner corner of the eye to prevent the drops from draining into your tear duct.
- Repeat as Directed: Follow the prescribed frequency and duration of use, usually three times daily.
Safety Concerns:
- May include some common side effects mild eye irritation, burning, or stinging upon application. These symptoms are generally temporary.
- Rarely, more severe reactions such as severe allergic reactions (e.g., rash, itching, and swelling) can occur.
- No significant interactions with other systemic medications are typically noted, but always inform your healthcare provider of all medications and supplements you are taking.
Avoid Besivance (Besifloxacin) If:
- You are allergic to besifloxacin or any other components of the eye drop formulation.
- You have a history of severe eye conditions or infections that may contraindicate the use of this medication.
- The safety of besifloxacin during pregnancy and lactation has not been well-studied. Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
