Save over 80% with brand name Janumet XR and up to 90% with the generic.
Click here for information on Sun Pharma generics (Immediate availability)
Information about Janumet XR (Sitagliptin/Metformin ER)
Janumet XR is an extended-release combination medication that contains sitagliptin, a DPP-4 inhibitor, and metformin, a biguanide. It is designed for the management of blood sugar levels in adults with type 2 diabetes and provides the convenience of once-daily dosing.
Product Highlights
- Sitagliptin increases incretin levels, enhancing insulin secretion and reducing glucagon levels, while metformin improves insulin sensitivity and reduces hepatic glucose production.
- To enhance blood sugar management in adults when diet and exercise are insufficient.
Key Ingredient
Key Benefits
- Convenient extended-release formulation allows for easier adherence to treatment.
- Effectively manages blood sugar levels.
- Generally weight-neutral, with some patients experiencing weight loss.
Direction of Use
- Typically taken once daily, with food, to reduce gastrointestinal side effects.
- Consistency in taking it at the same time each day is recommended for optimal results.
- Regular blood glucose monitoring and follow-up appointments are advised to evaluate effectiveness and side effects.
Safety Concerns
- Common side effects may include gastrointestinal issues (such as nausea, diarrhea), headache, and upper respiratory infections.
- Risk of lactic acidosis, especially in patients with renal impairment or dehydration.
- Patients should be monitored for signs of pancreatitis and allergic reactions.
Avoid Janumet XR (Sitagliptin/Metformin ER) If
- You have a known hypersensitivity to sitagliptin, metformin, or any components of the formulation.
- You have severe renal impairment, acute or chronic metabolic acidosis, or diabetic ketoacidosis.
- You are experiencing significant dehydration, serious infections, or conditions affecting kidney function.
