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Information about Jadenu (Deferasirox)
Jadenu is an oral medication used primarily to treat chronic iron overload due to blood transfusions in patients with conditions such as thalassemia or sickle cell disease. It contains the active ingredient deferasirox, which is a chelating agent that binds excess iron in the body, allowing it to be excreted.
Product Highlights
- Chronic iron overload resulting from frequent blood transfusions in patients with:
- Beta-thalassemia major
- Sickle cell disease
- Other anemias requiring repeated transfusions.
Key Ingredient
Key Benefits
- Effectively decreases excess iron, minimizing damage to vital organs (heart, liver, pancreas).
- Helps prevent complications associated with iron overload, such as organ dysfunction and diabetes.
- Convenient for adherence to treatment.
Direction of Use
- Administered once daily, typically on an empty stomach or at least 30 minutes before food.
- Tablets can be dispersed in water or juice before taking.
Safety Concerns
- Gastrointestinal disturbances (nausea, diarrhea), liver enzyme changes, renal impairment, and skin rashes.
- Regular monitoring of liver and kidney function, as well as blood counts, is recommended during treatment.
Avoid Jadenu (Deferasirox) If
- Known allergy to deferasirox or any component of the formulation.
- Not recommended for patients with severe renal dysfunction.
- Should be avoided unless the benefits outweigh risks; consult a healthcare provider.
- Caution is advised with concomitant use of specific medications that can affect kidney or liver function.
