Alimta (Pemetrexed)

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According to the European Medicines Agency, brand name Alimta originating from Europe is manufactured at the following site(s):Lilly France S.A.S. rue du Colonel Lilly F-67640 Fegersheim France

ALIMTA (Pemetrexed):

ALIMTA, or Pemetrexed, is us as powder for injection. ALIMTA is chemotherapy medication used primarily in the treatment of cancer:

• Non-small cell lung cancer (NSCLC)
• Mesothelioma (a cancer of the lining of the lungs and abdomen)

It is often used in combination with other chemotherapy drugs as determined by the healthcare provider.

Product Highlights

• Alimta is administered intravenously (IV), typically in a clinic or hospital setting.
• It is available as a powder that is reconstituted with sterile saline solution for IV infusion.

Key Ingredients

• Pemetrexed disodium

Key Benefits

• Alimta works by inhibiting several enzymes that are important in the synthesis of nucleotides (the building blocks of DNA and RNA), which are essential for cell replication.
• It is effective in slowing or stopping the growth of cancer cells, thereby helping to shrink tumors and alleviate cancer-related symptoms.
• Alimta has been shown to improve survival rates and quality of life in patients with NSCLC and mesothelioma when used as part of a comprehensive treatment plan.

Direction For Use

• Alimta is administered intravenously over a specific period, usually once every three weeks.
• The dosage and schedule are determined by the healthcare provider based on the patient's medical condition, weight, and other factors.
• Treatment typically involves pre-medication with certain medications (like corticosteroids and folic acid) to reduce the risk of side effects.

Safety Concern

• Alimta can cause a range of side effects, including fatigue, nausea, vomiting, decreased appetite, and low blood cell counts (which can increase the risk of infection or bleeding).
• It may also affect kidney function, so patients need regular monitoring of kidney function tests during treatment.
• Due to its potential for severe side effects, including bone marrow suppression and gastrointestinal toxicity, it should only be administered under the supervision of a healthcare provider experienced in chemotherapy administration.

Avoid Taking if ALIMTA (Pemetrexed):

• Alimta should be avoided in individuals with a known allergy to Pemetrexed or any of its components.
• It is not recommended for use in pregnant women due to potential harm to the fetus.
• Patients with severe kidney disease or impaired kidney function may also need dose adjustments or alternative treatments, as Alimta can worsen kidney function.