Information about Quisnon (Prulifloxacin)
Quisnon is a brand name for prulifloxacin, a second-generation fluoroquinolone antibiotic. It is primarily used to treat a variety of bacterial infections by inhibiting bacterial DNA replication, which prevents the growth and spread of bacteria. Prulifloxacin is particularly effective against gram-negative and gram-positive bacteria and is often used to treat infections of the urinary tract, gastrointestinal tract, and respiratory system. It is available in oral tablet form.
Product Highlights
- Used to treat uncomplicated or complicated urinary tract infections, including cystitis and pyelonephritis.
- Effective in treating gastrointestinal infections such as traveler's diarrhea and infections caused by Escherichia coli and other bacterial pathogens.
- Used to treat bacterial infections of the respiratory tract, including community-acquired pneumonia and acute exacerbations of chronic bronchitis.
- Can be used for other bacterial infections that are sensitive to prulifloxacin, depending on the culture and sensitivity results.
Key Ingredient
Key Benefits
- It is effective against a broad range of bacteria, including both gram-negative and gram-positive organisms.
- Primarily used for urinary, gastrointestinal, and respiratory infections, offering versatility in treating common bacterial diseases.
- Compared to some older fluoroquinolones, prulifloxacin tends to have fewer side effects.
- Taken orally, which makes it easier for patients to follow the treatment regimen.
- Prulifloxacin is effective against some strains of bacteria that have become resistant to other antibiotics.
Direction of Use
- Oral tablets.
- The standard dose for adults is one tablet (usually 300 mg) taken once daily, with or without food. The exact dosage and duration depend on the type and severity of the infection.
- The tablets should be taken whole with a sufficient amount of water. They should not be crushed or chewed.
- It is important to complete the full course of the antibiotic treatment, even if symptoms improve before the course is finished, to avoid antibiotic resistance.
Safety Concerns
- Frequent side effects include nausea, diarrhea, and stomach discomfort.
- Headaches, dizziness, and confusion can occur in some patients.
- Fluoroquinolones like prulifloxacin have been associated with an increased risk of tendonitis and tendon rupture, particularly in older adults.
- Prulifloxacin may cause prolongation of the QT interval on the ECG, which can lead to serious heart arrhythmias, especially when combined with other medications that affect the heart.
- Allergic reactions, including rash, itching, or swelling, may occur. Severe reactions, including anaphylaxis, are rare but possible.
- Prulifloxacin may affect blood sugar levels, especially in diabetic patients, leading to either hypoglycemia or hyperglycemia.
Avoid Quisnon (Prulifloxacin) If
- If you have a known allergy to prulifloxacin or any other fluoroquinolone antibiotics, you should avoid using this medication.
- Prulifloxacin should be avoided during pregnancy and breastfeeding unless the potential benefits exceed the risks. It is classified as a category C drug (not recommended during pregnancy unless absolutely necessary).
- If you have a history of tendon problems or joint disease, particularly if you are over 60 years of age, prulifloxacin should be used cautiously, as it can increase the risk of tendon rupture.
- If you have a history of heart arrhythmias or other cardiovascular conditions, prulifloxacin may not be safe, as it can prolong the QT interval and cause heart rhythm problems.
- Fluoroquinolones can lower the seizure threshold, so prulifloxacin should be avoided in individuals with a history of seizures or other neurological disorders.
- Prulifloxacin is primarily excreted via the kidneys, and in patients with severe renal or hepatic impairment, the drug may require dosage adjustments or should be avoided.
