Save 45% on Symproic from Europe.
Symproic is called Rizmoic in Europe.
Information about Symproic (Naldemedine)
Symproic (Naldemedine) is a prescription medication designed to treat opioid-induced constipation (OIC) in adults. It is an opioid receptor antagonist, designed to alleviate constipation caused by opioids while not affecting the pain-relieving effects of the opioid medication. Naldemedine works by blocking opioid receptors in the gastrointestinal (GI) tract, helping to restore normal bowel function without reversing the pain relief caused by opioids.
Product Highlights
- Symproic is primarily prescribed for the treatment of opioid-induced constipation in adult patients who are receiving opioid therapy for chronic pain and have not responded to laxative treatments.
Key Ingredient
Key Benefits
- Symproic helps to relieve constipation in adults taking opioids for chronic pain, improving bowel movements and reducing discomfort associated with opioid-induced constipation.
- Unlike traditional laxatives, Symproic works specifically in the gastrointestinal tract and does not affect the central nervous system, preserving the pain-relieving effects of opioids.
- Symproic is taken once daily, making it a simple and convenient option for managing OIC.
Direction of Use
- Symproic is taken by mouth in tablet form.
- The usual dose for adults is 0.2 mg taken once daily.
- It can be taken with or without food, according to your preference.
- If you miss a dose, take it as soon as you remember, unless it's nearly time for your next dose. Do not take two doses to compensate for a missed dose.
Safety Concerns
- The most common side effects of Symproic include abdominal pain, diarrhea, nausea, and flatulence.
- Some serious side effects include signs of an allergic reaction (rash, itching, swelling), severe abdominal pain, and vomiting. These should be reported to your healthcare provider right away.
- Symproic is metabolized in the liver, so individuals with liver impairment should use caution. Liver function tests may be required for patients with pre-existing liver conditions.
- Symproic may interact with other drugs, especially those that affect the liver enzymes (CYP450). It is important to inform your healthcare provider of all the medications you are currently taking.
Avoid Symproic (Naldemedine) If
- Symproic should be avoided in individuals who are allergic to naldemedine or any of its components.
- Symproic should not be used in patients with severe liver impairment due to potential risks related to liver metabolism and clearance.
- The safety of Symproic during pregnancy and breastfeeding has not been established. It should only be used during pregnancy if the potential benefits outweigh the risks, and it is not recommended for breastfeeding mothers.
- Symproic should be avoided in patients with known or suspected gastrointestinal obstruction.
