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Information about Viberzi (Eluxadoline)
Viberzi is a medication that contains Eluxadoline as its active ingredient. It is used to treat irritable bowel syndrome with diarrhea (IBS-D) in adults. Eluxadoline works by acting on receptors in the gastrointestinal tract to reduce muscle contractions and the speed of bowel movements, helping to alleviate symptoms like diarrhea, urgency, and discomfort associated with IBS-D.
Product Highlights
- A condition characterized by chronic diarrhea, abdominal pain, and bloating.
- Eluxadoline helps reduce symptoms such as diarrhea and abdominal discomfort in adult patients with IBS-D.
Key Ingredient
Key Benefits
- Eluxadoline is effective in managing IBS-D symptoms, including diarrhea, urgency, and discomfort.
- By slowing down bowel movement, it decreases the frequency of diarrhea, a key symptom of IBS-D.
- Eluxadoline reduces abdominal discomfort and cramping associated with IBS-D.
- Many patients tolerate Viberzi well, especially when used as prescribed.
Direction of Use
- Viberzi should be taken twice daily, with or without food.
- The usual dose is 100 mg, although the dosage may be adjusted depending on individual tolerance and effectiveness.
- It should be swallowed whole with water and not chewed, crushed, or split.
- If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose.
- Start with a lower dose (e.g., 75 mg) for patients who are at increased risk of side effects, such as those with liver issues.
Safety Concerns
- Eluxadoline can increase the risk of pancreatitis, a serious condition that causes inflammation of the pancreas. Pancreatitis symptoms may include intense abdominal pain, nausea, and vomiting.
- Eluxadoline is metabolized by the liver, and it may cause liver issues. Liver function tests should be monitored, particularly in patients with liver disease.
- Overuse or misuse of Eluxadoline can lead to severe constipation or gastrointestinal problems.
- Eluxadoline should be used with caution or avoided in patients with a history of alcoholism, gallstones, or severe liver disease.
- Because Eluxadoline is a mixed opioid receptor agonist, it may cause opioid-like side effects, such as sedation, dizziness, and nausea.
Avoid Viberzi (Eluxadoline) If
- You have a history of pancreatitis, or you have active gallbladder disease (e.g., gallstones).
- You have severe liver problems, such as cirrhosis or liver impairment.
- You have a history of alcohol abuse or are a chronic heavy drinker.
- You have a blocked or narrowed bowel (e.g., intestinal obstruction).
- You have a history of opioid abuse or have used opioid medications in a way other than prescribed.
- You are allergic to Eluxadoline or any of the other ingredients in Viberzi.
- You have a severe constipation problem, or you are prone to constipation.
- You are pregnant or breastfeeding (consult with a doctor, as the safety of Eluxadoline during pregnancy and lactation is not well established).
