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Information about Trixeo Inhaler
Trixeo Inhaler is a fixed-dose combination product that contains three active ingredients: Budesonide, Glycopyrronium, and Formoterol fumarate. These ingredients work together to relieve symptoms of COPD and help manage the condition over time. Budesonide is a corticosteroid, Glycopyrronium is a long-acting muscarinic antagonist (LAMA), and Formoterol fumarate is a long-acting beta-agonist (LABA). These three drugs target different mechanisms involved in inflammation and airway constriction to improve airflow and reduce symptoms.
Product Highlights
- Trixeo is primarily indicated for the long-term maintenance treatment of COPD in adults.
- It may also be used in managing these conditions when they occur as part of COPD.
Key Ingredients
- A corticosteroid that helps reduce inflammation in the airways, thus preventing flare-ups and improving symptoms over time.
- A long-acting muscarinic antagonist (LAMA) that helps to relax and open the airways by blocking certain receptors in the lungs.
- A long-acting beta-agonist (LABA) that works by stimulating beta receptors in the lungs to relax the airway muscles, which helps to keep the airways open.
Key Benefits
- The combination of a corticosteroid and bronchodilators helps ease breathing by reducing airway inflammation and keeping the airways open.
- Trixeo provides 24-hour relief from COPD symptoms with once-daily use, improving patient adherence.
- The anti-inflammatory action of Budesonide helps reduce the frequency and severity of COPD exacerbations.
- The inhaler provides a simple and effective treatment regimen, combining three medications in a single device.
Direction of Use
- The typical dosage for adults is one inhalation per day, usually taken in the morning.
- Inhale the medication through the mouth using the Trixeo inhaler as directed. Make sure to follow the inhaler instructions carefully to ensure correct administration.
- If using the inhaler for the first time, or if it hasn't been used in more than 7 days, prime it before use.
- It is important to use the inhaler at the same time each day to ensure consistent effectiveness.
- Do not use more than one inhalation per day unless advised by a healthcare provider.
Safety Concerns
- Common side effects may include throat irritation, headache, and mouth dryness. Serious side effects like increased risk of pneumonia, cardiovascular issues, or adrenal suppression can occur with long-term use.
- In rare cases, the inhaler may cause paradoxical bronchospasm (a sudden tightening of the airways), which can worsen symptoms.
- As with other inhaled corticosteroids, there is a risk of fungal infections in the mouth or throat (e.g., oral thrush), so regular mouth rinsing after inhalation is recommended.
- Use of inhaled corticosteroids can have systemic effects like affecting bone density, eyes (increased intraocular pressure), and the immune system.
Avoid Trixeo Inhaler If
- You are allergic to Budesonide, Glycopyrronium, Formoterol, or any other component of the Trixeo inhaler.
- You have a history of severe allergic reactions (e.g., anaphylaxis) to any of the inhaler’s ingredients.
- You have acute bronchospasm or need a rescue inhaler for rapid relief of symptoms (Trixeo is not meant for immediate relief of sudden breathing difficulties).
- You are pregnant or breastfeeding, unless advised otherwise by your healthcare provider.
- You have a history of cardiovascular disease, including certain heart conditions, as the LABA component (Formoterol) may increase heart rate and affect heart rhythm.