Save almost 50% from US Retevmo prices. Retevmo is called Retsevmo in Europe.
Non-english packaging - English label and English insert included. Plan in advance - allow us 7 days to ship your medicine
Manufacturer for European products:
Lilly S.A., Avda. de la Industria 30, 28108 Alcobendas, Madrid, Spain
Information about Retevmo (Selpercatinib)
Retevmo (generic name Selpercatinib) is a prescription medication that belongs to a class of drugs known as tyrosine kinase inhibitors. It is used to treat certain types of cancer that have specific genetic mutations. Retevmo works by targeting and blocking specific abnormal proteins that promote the growth of cancer cells. This medication is primarily used for treating non-small cell lung cancer (NSCLC) and other cancers with RET (rearranged during transfection) gene mutations.
Product Highlights
- Specifically for patients whose cancer cells carry RET gene mutations. It can be used as a first-line treatment or after other treatments fail.
- For patients with advanced medullary thyroid cancer (MTC) or thyroid cancers with RET mutations who are not candidates for surgery.
- Retevmo is also indicated for certain cancers where RET gene mutations are present, including some cases of cancer that involve the brain, liver, or other organs.
Key Ingredient
Key Benefits
- Retevmo specifically targets and blocks the RET protein, slowing or stopping cancer cell growth in patients with RET-positive cancers.
- Proven efficacy in treating non-small cell lung cancer, thyroid cancer, and other cancers with RET gene alterations.
- Clinical studies have shown that Retevmo can improve progression-free survival and overall response rates in patients with RET-positive cancers.
- Offers a convenient oral alternative to traditional chemotherapy, which often requires intravenous administration.
- Compared to conventional chemotherapy, Retevmo tends to have a more favorable side-effect profile for certain patients.
Direction of Use
- Retevmo is taken orally, usually in the form of a capsule.
- The usual starting dose is based on the patient's condition, weight, and tolerability. It is typically administered twice daily, but the dosage may vary.
- It is essential to take Retevmo at the same times every day to ensure a consistent level of the medication in your body.
- Retevmo can be taken with or without food, as food does not significantly impact its absorption.
- If you miss a dose, take it as soon as you can, unless it's nearly time for your next dose. In that case, skip the missed dose and proceed with your regular dosing schedule.
Safety Concerns
- Retevmo may affect liver function, so liver tests should be performed regularly during treatment. Liver toxicity or elevated liver enzymes could require dose adjustments or discontinuation.
- Retevmo can cause QT interval prolongation, which may increase the risk of life-threatening heart arrhythmias. Monitoring of heart function is recommended.
- Some patients may develop high blood pressure during treatment, which should be managed and monitored regularly.
- As with many cancer treatments, Retevmo may increase the risk of bleeding, including serious or fatal bleeding events.
- Retevmo can affect the body’s ability to heal wounds, so it should be used cautiously in patients who have recently undergone surgery.
- Common side effects include fatigue, diarrhea, nausea, liver enzyme abnormalities, and hypertension. More serious side effects may include severe liver problems and heart-related issues.
Avoid Retevmo (Selpercatinib) If
- You are allergic to Selpercatinib or any of the ingredients in Retevmo.
- You have a history of QT prolongation or other heart conditions that could be worsened by this drug.
- You have severe liver impairment, as Retevmo can cause liver toxicity.
- You are pregnant or breastfeeding, unless advised by your healthcare provider, as Retevmo may harm a developing fetus or newborn.
- You have a history of bleeding disorders, as Retevmo may increase the risk of bleeding.
- You are having surgery or have recently undergone surgery, as Retevmo may affect wound healing.
