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Information about Emflaza (Deflazacort)
Emflaza is a corticosteroid used primarily in the treatment of Duchenne muscular dystrophy (DMD), a genetic disorder that causes progressive muscle weakness. It contains the active ingredient deflazacort, which works by reducing inflammation and modulating immune system activity. Emflaza is often considered an alternative to prednisone, with potentially fewer side effects, especially related to weight gain.
Product Highlights
- Emflaza is approved for the treatment of DMD in patients aged 2 years and older.
- It helps improve muscle strength, function, and delay the progression of disease in these patients.
Key Ingredient:
Key Benefits
- Emflaza has been shown to improve muscle strength in patients with DMD, helping them maintain mobility for a longer period.
- It can help delay the loss of muscle function, thereby preserving quality of life in patients with DMD.
- Compared to other corticosteroids like prednisone, deflazacort may have a lower incidence of weight gain, cataracts, and other typical steroid-related side effects.
- By maintaining muscle strength, Emflaza can indirectly help with respiratory function as well, as strong respiratory muscles are important for breathing.
Direction of Use
- Emflaza is usually administered orally in the form of a tablet or suspension. The dosage is typically based on body weight and is given once a day.
- It is recommended to take Emflaza with food to reduce gastrointestinal upset. Always follow your doctor’s specific instructions for the correct dosage and administration schedule.
Safety Concerns
- Like all corticosteroids, Emflaza can cause side effects, including weight gain, fluid retention, increased blood pressure, cataracts, and osteoporosis. Regular monitoring by a healthcare provider is essential.
- Prolonged use of corticosteroids can weaken the immune system, making patients more susceptible to infections.
- In children, long-term use of deflazacort may affect growth. It’s essential to regularly monitor the growth of pediatric patients.
Avoid Emflaza (Deflazacort) If
- Avoid use if you have a known allergy to deflazacort or other corticosteroids.
- If you have active fungal, viral, or bacterial infections, corticosteroids like Emflaza may worsen the condition.
- If you have uncontrolled diabetes, peptic ulcers, or severe heart, kidney, or liver issues, Emflaza should be avoided or used with extreme caution under medical supervision.
- While Emflaza should only be used during pregnancy if absolutely necessary, and with caution during breastfeeding, consult your doctor if you're pregnant, planning to become pregnant, or breastfeeding.
