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Product Details

Kalydeco

Save 23% on Kalydeco from Europe.

Non-english packaging is often present for European medicines- English label and English insert included. Plan in advance - allow us 7 days to ship this brand name medicine.

According to the European Medicines Agency, brand name Kalydeco originating from Europe is manufactured at the following site(s):Almac Pharma Services (Ireland) Limited Finnabair Industrial Estate Dundalk Co. Louth A91 P9KD IrelandAlmac Pharma Services Limited Seagoe Industrial Estate Craigavon Northern Ireland BT63 5UA United KingdomMillmount Healthcare Limited Block-7, City North Business Campus,K32 YD60 Ireland Stamullen Co. Meath

Information about Kalydeco (Ivacaftor)

Kalydeco is a medication used to treat cystic fibrosis in patients with specific mutations in the CFTR gene. It is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator that helps improve the function of the defective CFTR protein.

Product Highlights

Treatment of cystic fibrosis in patients aged 6 months and older who have one of the following mutations: G551D or other specific mutations in the CFTR gene.

Key Ingredient

Ivacaftor

Key Benefits

Enhances chloride transport in epithelial cells, leading to improved lung function and reduced pulmonary exacerbations.
May improve overall health and quality of life for patients with cystic fibrosis.
Specifically designed for patients with certain CFTR mutations, offering a personalized treatment approach.

Direction of Use

Take Kalydeco exactly as prescribed by your healthcare provider, usually twice daily.
It should be taken alongside food to optimize absorption.
Follow the specific dosing instructions based on the patient's age and weight.

Recommended Dosage in Pediatric Patients Aged 1 Month to Less than 6 Years

Recommended Dosage of KALYDECO Oral Granules by Body Weight in Pediatric Patients Aged 1 month to less than 6 Years
Age	Body Weight (kg)	KALYDECO Dosage
1 month to less than 2 months	3 kg or greater	One packet (containing 5.8 mg ivacaftor) every 12 hours
2 months to less than 4 months	3 kg or greater	One packet (containing 13.4 mg ivacaftor) every 12 hours
4 months to less than 6 months	5 kg or greater	One packet (containing 25 mg ivacaftor) every 12 hours
6 months to less than 6 years of age	5 kg to less than 7 kg	One packet (containing 25 mg ivacaftor) every 12 hours


7 kg to less than 14 kg	One packet (containing 50 mg ivacaftor) every 12 hours
14 kg or greater	One packet (containing 75 mg ivacaftor) every 12 hours

Safety Concerns

Common side effects include headache, sore throat, and abdominal pain.
Serious side effects can include liver enzyme elevations and respiratory symptoms.
Frequent monitoring of liver function tests may be necessary.

Avoid Kalydeco (Ivacaftor) If

You have a known hypersensitivity to ivacaftor or any of its components.
You have severe liver disease or significant liver impairment.
You are taking medications that may interact adversely, such as strong CYP3A inhibitors.

Kalydeco (Ivacaftor)

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