Apretude (Cabotegravir)

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Brand Name : Apretude

Marketing Authorization Holder : ViiV Healthcare

Prescription Required

 
 
No Generic Medicine available for this medicine.

Product Details

Apretude

Save 35% on Apretude injection. It is known as Vocabria injection in Europe. 

Non-english packaging is often present for European medicines- English label and English insert included. Plan in advance - allow us 7 days to ship this brand name medicine.

According to the European Medicines Agency, brand name Vocabria originating from Europe is manufactured at the following site(s):Glaxo Wellcome, S.A. Avda. Extremadura, 3 Aranda De Duero Burgos 09400 Spain

Information about Apretude (Cabotegravir)

Apretude is a medication used for the prevention of HIV infection. Specifically, it is used as pre-exposure prophylaxis (PrEP) to reduce the risk of acquiring HIV in individuals who are at high risk of infection. 

Cabotegravir is active ingredient in Apretude. Cabotegravir is an integrase strand transfer inhibitor (INSTI) that works by preventing the HIV virus from integrating into the DNA of host cells, thereby stopping its replication.

Product Highlights

  • Apretude is available as an injectable formulation.
  • It is administered as an injection every 2 months (bi-monthly) after an initial loading dose.
  • It is approved for use in several countries, including the United States, and is generally recommended for individuals who are HIV-negative and at high risk of contracting HIV.

Key Ingredients

  • Cabotegravir

Key Benefits

  • Provides strong protection against HIV when used as prescribed.
  • The bi-monthly injection reduces the need for daily oral medication, which can improve adherence and convenience for patients.
  • Clinical studies have shown that Apretude is highly effective in preventing HIV infection in high-risk populations.

Direction For Use

  • Usually, an initial loading dose is administered, followed by maintenance doses every 2 months.
  • The injection is given intramuscularly (into the muscle) by a healthcare professional.
  • It is crucial to adhere to the dosing schedule to maintain effective levels of the medication in the body.

Recommended Dosing Schedule (Direct to Injection) for Pre-exposure Prophylaxis in Adults and Adolescents Weighing at Least 35 kg.

Intramuscular (Gluteal) Initiation Injection (Month 1 and Month 2)Intramuscular (Gluteal) Continuation Injection (Month 4 and Every 2 Months Onwards)
APRETUDEa 600 mg (3 mL)APRETUDEa 600 mg (3 mL)

Safety Concern

  • Possible side effects include injection site reactions, fever, fatigue, headache, and gastrointestinal symptoms. Most side effects are mild to moderate.
  • Regular follow-ups with a healthcare provider are recommended to monitor for any adverse effects and to ensure continued effectiveness of the medication.
  • In rare cases, serious allergic reactions may occur. Immediate medical attention is required if symptoms like rash, itching, or swelling occur.

Avoid Apretude (Cabotegravir) If

  • If you are already HIV-positive, Apretude is not appropriate as it is intended for those who are HIV-negative.
  • If you have a known severe allergic reaction to cabotegravir or any of its components, you should avoid using this medication.
  • Individuals with certain health conditions, such as severe liver impairment, may need to avoid or use this medication with caution. Always consult a healthcare provider to ensure it is safe based on individual health conditions and other medications being taken.

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