Xigduo XR (Dapagliflozin / Metformin)

Save over 83% with brand Xigduo from USA (Pfizer)

Prescription Xigduo XR is a convenient 2 in 1 tablet combining Dapagliflozin and Metformin.  Xigduo XR is used by type 2 diabetics to lower blood sugar and A1C levels in your blood.   Xigduo XR is prescribed alongside of a good diet and plenty of exercise.

Xigduo XR lowers A1C much more than metformin does on its own.  Xigduo XR also causes weight loss an average of 3% and lowers systolic blood pressure as an additional benefit.

Xigduo XR is a once daily medicine, usually taken first thing in the morning with your breakfast.

Xigduo XR works by causing your digestive system to absorb less sugar, causes your liver to make less sugar, and removes more sugar via your urine.  Xigduo XR also helps you create your own natural insulin to combat diabetes.

Monitor your blood sugar with a blood sugar diary.  Document your sugar levels regularly and the types of food you eat as well as the amount of physical activity you participate in.  Doing so, will help you reach your blood sugar goal.  Plan your meals and eat healthy, stay active, take all medicines as your doctor prescribes and monitor your blood sugar levels.

Because Xigduo XR works through your kidneys, do not use if you are on dialysis or have moderate to severe kidney disease.

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Information about Xigduo XR (Dapagliflozin / Metformin)

Xigduo XR is a combination medication that combines two active ingredients: dapagliflozin and metformin. This medication is primarily used to manage type 2 diabetes by helping to control blood sugar levels. Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor, which works by preventing the kidneys from reabsorbing glucose, thus promoting the excretion of glucose in urine. Metformin is a biguanide that works by improving insulin sensitivity and reducing glucose production in the liver. Together, these drugs help manage blood sugar more effectively in patients with type 2 diabetes.

Product Highlights

• Xigduo XR is indicated for the treatment of type 2 diabetes to help improve glycemic control in conjunction with diet and exercise.
• This combination is often used when diet and exercise alone do not adequately control blood sugar levels in patients with type 2 diabetes.

Key Ingredient

• Dapagliflozin
• Metformin

Key Benefits

• Xigduo XR helps to lower and control blood sugar levels in people with type 2 diabetes.
• Dapagliflozin may promote mild weight loss in some patients, which is beneficial for people with type 2 diabetes who are overweight.
• Dapagliflozin has been shown to have beneficial effects on cardiovascular health, which is important for people with type 2 diabetes who are at an increased risk of heart disease.
• As an extended-release formulation, Xigduo XR provides the convenience of once-daily dosing, making it easier for patients to manage their treatment regimen.

Direction of Use

• The typical starting dose of Xigduo XR is usually 5 mg/1000 mg or 10 mg/1000 mg once daily with the evening meal. Your doctor may adjust the dose based on your individual needs and blood sugar control.
• Swallow the tablet whole with a meal to reduce the risk of gastrointestinal side effects. Do not crush, chew, or break the tablet.
• Regular monitoring of blood sugar levels and kidney function is important while taking Xigduo XR to ensure the medication is effective and safe.

Safety Concerns

• Xigduo XR may not be suitable for people with severe kidney problems. Kidney function should be monitored regularly during treatment.
• Due to the effect of dapagliflozin on the kidneys, dehydration and low blood pressure can occur. Patients should stay hydrated and monitor for signs of dehydration.
• Metformin has a rare but serious risk of lactic acidosis, a potentially life-threatening condition. Symptoms include muscle pain, difficulty breathing, and tiredness. If these occur, immediate medical attention is needed.
• Dapagliflozin increases the risk of genital infections, particularly in women. Good hygiene is important, and any symptoms should be promptly addressed by a doctor.
• The risk of urinary tract infections may be increased due to the action of dapagliflozin in increasing glucose in the urine. Patients should seek medical advice if they experience symptoms of UTIs.
• Although Xigduo XR itself does not usually cause low blood sugar, the risk of hypoglycemia can increase when combined with other medications that lower blood sugar, such as insulin or sulfonylureas.

Avoid Xigduo XR (Dapagliflozin / Metformin) If

• If you have severe kidney disease or if your kidneys are not functioning properly, you should not take Xigduo XR.
• Avoid using Xigduo XR if you have metabolic acidosis, including diabetic ketoacidosis (DKA).
• If you have severe liver disease, your doctor may recommend an alternative treatment, as Xigduo XR may not be appropriate.
• If you have had a hypersensitivity reaction (such as a severe allergic reaction) to dapagliflozin, metformin, or any other ingredients in Xigduo XR, do not use this medication.
• Xigduo XR is not recommended during pregnancy, and it should only be used if necessary while breastfeeding. Speak with your doctor for alternatives.
• If you have severe heart failure, especially if you are at risk for fluid retention, you should discuss treatment options with your healthcare provider.