Janumet (Sitagliptin / Metformin)

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Brand Name : Janumet

Marketing Authorization Holder : Merck Sharp & Dohme

Prescription Required

 
 

Generic Option

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Generic Name : Sitagliptin / Metformin

Manufactured By : Authorized Indian Generic

Prescription Required

 
 

Product Details

Janumet

Save 75% on brand name Janumet and 90% with the generic Janumet.

In the United Kingdom, Janumet (sitagliptin / metformin) is available in the single strength of 50mg/1000mg, not the smaller dose of 50mg/500mg.

Prescription Janumet is used to treat type 2 diabetes in adults to improve blood sugar levels and A1C levels alongside of exercise and a good diet plan.

Janumet is often given to patients who are not getting satisfactory results from metformin alone or are already taking these medicines in 2 separate tablets (Januvia and Glucophage). Janumet can also be added to insulin or other antidiabetic medicine, however doses of other medicines may need to be decreased when adding Janumet.

Janumet causes an increase in natural insulin production when sugar is too high, reduces the amount of sugar made by the liver, and prevents sugar absorption in the gut.

Janumet is given twice daily only, with food to avoid stomach side effects.

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Information about Janumet (Sitagliptin / Metformin)

Janumet is a combination medication that combines sitagliptin, a DPP-4 inhibitor, with metformin, a biguanide. It is employed to better manage blood sugar levels in adults with type 2 diabetes.

Product Highlights

  • Sitagliptin increases incretin levels, which helps to increase insulin release and decrease glucagon levels. Metformin enhances insulin sensitivity and decreases glucose production in the liver.
  • To improve blood sugar control in adults when diet and exercise alone are insufficient.

Key Ingredient

  • Sitagliptin
  • Metformin

Key Benefits

  • Helps lower blood sugar levels effectively.
  • Generally does not cause weight gain, and some patients may even lose weight.
  • The combination of two medications in one tablet simplifies treatment regimens.

Direction of Use

  • Typically, 50 mg of sitagliptin and 500 mg to 1000 mg of metformin taken twice daily.
  • It should be taken with food to help minimize gastrointestinal side effects.
  • Regular blood glucose monitoring and follow-up appointments to assess effectiveness and side effects.

Safety Concerns

  • Common side effects may include gastrointestinal issues (nausea, diarrhea), headache, and upper respiratory infections.
  • Risk of lactic acidosis, particularly in patients with renal impairment or dehydration.
  • Patients should be monitored for potential allergic reactions and pancreatitis.

Avoid Janumet (Sitagliptin / Metformin) If

  • You have a known hypersensitivity to sitagliptin, metformin, or any components of the formulation.
  • You have severe renal impairment or acute or chronic metabolic acidosis, including diabetic ketoacidosis.
  • You are experiencing a serious infection, dehydration, or any condition that may affect kidney function.


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