Januvia (Sitagliptin)

Prescription Januvia is used by adults for the treatment of type 2 diabetes along with a good exercise program and healthy diet.  Januvia lowers blood sugar and brings down you A1C levels. Januvia is often taken by people already taking metformin as Januvia works well with metformin to lower A1C levels further.

Januvia is not used to treat type 1 diabetes or diabetic ketoacidosis. If you have ever had inflammation of the pancreas (pancreatitis), you may not be eligible to take Januvia.

Januvia works by lowering your blood sugar when the levels are too high and when blood sugar is already low, Januvia has less effect.  This way Januvia moderates blood sugar levels.

Januvia is taken once daily, at the same time each day, without regards to food (with or without food).  Take Januvia exactly as directed by your doctor. If you miss a dose of Januvia, take once you remember unless it is already time for your next dose. Never take 2 doses of Januvia at once.

While taking Januvia, your physician may conduct tests to see how your kidneys are functioning. Your dose of Januvia may change as a result of the tests. You may be prescribed Januvia along with other diabetes medications and if so, you need to be monitoring your sugar in case it goes too low.

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Information about Januvia (Sitagliptin)

Januvia is an oral medication that contains sitagliptin, a DPP-4 inhibitor used to improve glycemic control in adults with type 2 diabetes. It works by increasing the levels of incretin hormones, which help regulate blood sugar levels.

Product Highlights

• Inhibits the enzyme DPP-4, leading to increased incretin levels, which enhances insulin secretion and decreases glucagon levels.
• To improve blood sugar control in adults when diet and exercise are not sufficient.

Key Ingredient

• Sitagliptin

Key Benefits

• Helps lower blood sugar levels and improve overall diabetes management.
• Generally does not cause weight gain and may be weight-neutral.
• Convenient dosing regimen simplifies treatment adherence.

Direction of Use

• Typically 100 mg once daily; dosages may vary based on individual needs.
• Can be taken at any time of day, regardless of meals.
• Regular blood glucose monitoring and follow-up appointments are essential to assess effectiveness and any side effects.

Dosage adjustment is advised for patients with moderate to severe renal insufficiency or end-stage renal disease.

Safety Concerns

• Common side effects may include upper respiratory tract infections, headache, and gastrointestinal issues (nausea, diarrhea).
• Risk of pancreatitis and allergic reactions; patients should be monitored for signs of these conditions.
• Patients with renal impairment should be treated with caution.

Avoid Januvia (Sitagliptin) If

• You have a known hypersensitivity to sitagliptin or any components of the formulation.
• You have a history of severe allergic reactions or pancreatitis.
• You have significant renal impairment or are on dialysis.