Information about Glucophage XR (Metformin ER)
Glucophage XR is an extended-release formulation of metformin, an oral antihyperglycemic agent used primarily for managing blood sugar levels in individuals with type 2 diabetes. This formulation allows for once-daily dosing, improving patient adherence and reducing gastrointestinal side effects.
Product Highlights
- Indicated for the management of blood glucose levels in adults and children over 10 years old.
- Sometimes used off-label to help manage symptoms associated with PCOS.
Key Ingredient
Key Benefits
- Helps lower and maintain healthy blood glucose levels.
- Extended-release formulation allows for once-daily administration, which can enhance adherence.
- Generally does not cause weight gain and may assist in weight management.
Direction of Use
- Typically initiated at a low dose and gradually increased based on individual response and tolerance.
- Taken orally, usually with the evening meal to minimize gastrointestinal side effects.
- The tablet should not be crushed or chewed.
Safety Concerns
- Frequent side effects may include nausea, diarrhea, and stomach discomfort.
- A rare yet serious condition, especially in individuals with reduced kidney function.
- Extended use may result in reduced absorption of vitamin B12.
Avoid Glucophage XR (Metformin ER) If
- You have a known allergy to metformin or any of its components.
- Contraindicated in patients with significant renal impairment (eGFR < 30 mL/min).
- Including conditions like diabetic ketoacidosis or lactic acidosis.
- Should be avoided in patients with significant hepatic dysfunction, increasing the risk of lactic acidosis.
