Information about Glucophage (Metformin)
Glucophage is an oral medication that contains metformin, which is primarily used to manage blood sugar levels in individuals with type 2 diabetes. It enhances insulin sensitivity and lowers glucose production in the liver.
Product Highlights
- Used to improve glycemic control in adults and children over 10 years old.
- Sometimes used off-label to manage symptoms associated with PCOS.
Key Ingredient
Key Benefits
- Aids in reducing and stabilizing blood glucose levels.
- Typically does not cause weight gain and may help with weight loss.
- Less likely to induce low blood sugar than many other diabetes medications.
Direction of Use
- Doses typically start low and are gradually increased based on blood sugar levels and tolerance.
- Taken orally, usually in divided doses with meals to reduce gastrointestinal side effects.
- Taken once daily, usually with the evening meal.
Safety Concerns
- Frequent side effects include nausea, diarrhea, and stomach discomfort.
- A rare but serious side effect, especially in patients with renal impairment.
- Long-term use may lead to decreased absorption of vitamin B12.
Avoid Glucophage (Metformin) If
- You have a known allergy to metformin or any of its components.
- Contraindicated in patients with significant renal impairment (eGFR < 30 mL/min).
- Including diabetic ketoacidosis or lactic acidosis.
- Should be avoided in patients with hepatic dysfunction, as it increases the risk of lactic acidosis.
