Dipentum (Olsalazine)

Dipentum in the United Kingdom is available in 250mg and 500mg strengths. In the UK, there is generic Dipentum available at substantial savings.  Generic Dipentum is equivalent to brand Dipentum and completely interchangeable.

Prescription Dipentum (olsalazine) is used in the treatment of ulcerative colitis, a disease of the bowels.  Dipentum is not a cure but blocks inflammation and symptoms like abdominal pain, diarrhea and rectal bleeds caused the swelling and irritation of the colon and rectum.  Dipentum increased the time between attacks, and causing relief from the symptoms. Dipentum will thus allow more time for your gut to heal.

Dipentum is classified as a salicylate, an anti-inflammatory. Dipentum is believed to block prostaglandin synthesis that can cause pain and swelling.

The Dipentum dose is usually twice daily (12 hours apart), taken with food or just afterwards to prevent upset stomach.  Your doctor will determine the best possible dose of Dipentum for your condition. Take Dipentum at the same time each day and if you forget a dose, take as soon as possible unless your next dose is approaching. Never take double doses of Dipentum.

When you begin treatment with Dipentum, you may start with only 250mg but have the dose increased over time. The standard dose is 500mg Dipentum twice per day and higher doses perhaps when your condition flares up. Dipentum begins to work immediately but may take time to reach its optimum effect and even months for your gut to heal.

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Information about Dipentum (Olsalazine)

Dipentum is a brand name for the drug olsalazine, which is a type of 5-aminosalicylic acid (5-ASA) compound. It is used primarily to treat inflammatory bowel diseases (IBD), particularly ulcerative colitis. Olsalazine works by reducing inflammation in the colon.

Product Highlights

• To maintain remission and manage symptoms of ulcerative colitis, a type of inflammatory bowel disease that affects the colon.
• May be used as part of a broader treatment regimen for inflammatory bowel diseases involving the colon.

Key Ingredient

• Olsalazine 

Key Benefits:

• Helps reduce inflammation in the colon, leading to symptom relief and maintenance of remission in ulcerative colitis.
• Can help reduce symptoms such as diarrhea, rectal bleeding, and abdominal pain.
• Assists in long-term management of ulcerative colitis, potentially reducing flare-ups and improving quality of life.

Direction of Use

• Follow the dosage prescribed by your healthcare provider, commonly starting with one or two 250 mg tablets taken twice daily. The exact dosage may be adjusted based on your response and condition.
• Swallow the tablets whole with water. They can be taken regardless of meals.
• Take at the same time each day to help remember your doses and maintain effective medication levels.

Safety Concerns

• May include diarrhea, abdominal pain, nausea, or headache.
• Can include allergic reactions, liver function abnormalities, and severe gastrointestinal symptoms.
• Regular monitoring by your healthcare provider may be necessary to assess liver function and the effectiveness of the treatment.

Avoid Dipentum (Olsalazine) If

• You have a known allergy to olsalazine or any other components of the medication.
• Avoid if you have severe kidney impairment, as the medication may affect kidney function.
• If you have severe liver disease or active liver dysfunction, caution is advised or alternative treatments may be considered.
• If you have a history of drug-induced colitis or severe gastrointestinal reactions to 5-ASA compounds, use with caution.