Uceris (Budesonide ER)

Uceris is called Cortiment in Europe.

Information about Uceris (Budesonide ER)

Uceris is a brand name for the extended-release (ER) formulation of budesonide, which is a corticosteroid medication. It is used primarily for treating ulcerative colitis, a condition that causes inflammation and sores in the digestive tract. Uceris is designed to release budesonide gradually over time, targeting the colon to reduce inflammation and symptoms.

Product Highlights

• Uceris is primarily used to treat active, mild-to-moderate cases of ulcerative colitis in adults, aiming to reduce inflammation and control flare-ups.

Key Ingredient

• Budesonide

Key Benefits

• Uceris helps reduce the inflammation associated with ulcerative colitis, leading to symptom relief (such as abdominal pain, diarrhea, and rectal bleeding).
• The extended-release formulation targets the colon specifically, helping to reduce side effects compared to systemic corticosteroids.
• It’s typically taken once a day, improving patient compliance.

Direction of Use

• Uceris is usually taken once daily in the morning, with or without food.
• The tablets should not be crushed, chewed, or broken, as this would interfere with the extended-release mechanism.
• The treatment duration may vary, but it’s typically used for a short period to control active disease, with ongoing maintenance therapy potentially required.

Safety Concerns

• Like other corticosteroids, long-term use of Uceris can lead to side effects such as osteoporosis, cataracts, and adrenal suppression. Regular monitoring may be required.
• Although Uceris is designed for localized action, some systemic absorption may still occur, leading to possible side effects common with corticosteroids.
• Uceris can suppress the immune system, making it more difficult for your body to fight infections.

Avoid Uceris (Budesonide ER) If

• Patients with a known hypersensitivity to budesonide or other ingredients in Uceris should avoid the medication.
• Uceris should not be used in individuals with systemic fungal infections, as corticosteroids can worsen infections.
• If you have any uncontrolled or serious infections, avoid using Uceris until the infection is appropriately treated.
• Severe liver impairment may affect how the body processes Uceris, so it should be avoided or used with caution in those with significant liver issues.