Information about Entocort (Budesonide ER)
Entocort EC is a prescription medication that contains budesonide, a corticosteroid used to reduce inflammation in the gastrointestinal tract. It is formulated as an extended-release capsule to deliver the medication specifically to the ileum and ascending colon.
Product Highlights
- This medication is primarily indicated for the treatment of mild to moderate Crohn’s disease, particularly when it affects the ileum and/or ascending colon.
- It is also used to help maintain remission in patients with Crohn’s disease and may be used off-label for other inflammatory bowel conditions under the guidance of a specialist.
Key Ingredient
Key Benefits
- Entocort effectively reduces inflammation in the intestines, making it useful for managing symptoms of Crohn’s disease.
- It helps induce and maintain remission, and because of its targeted delivery system, it results in fewer systemic side effects compared to traditional corticosteroids such as prednisone.
- By acting mainly in the affected areas of the gut, it limits exposure to the rest of the body.
Direction of Use
- The typical dosage is one 3 mg capsule taken once to three times daily, depending on the severity of the condition and the treatment phase.
- It is usually taken in the morning, preferably before breakfast.
- The capsule should be swallowed whole with water and must not be crushed or chewed.
- The exact dosage and duration should always be determined and monitored by a healthcare professional.
Safety Concerns
- Long-term use of Entocort may cause adrenal suppression, so tapering may be necessary when discontinuing the medication.
- It can also increase the risk of infections due to its immunosuppressive effects. Other possible long-term side effects include bone thinning, blood sugar changes, and eye problems such as cataracts.
- Budesonide levels in the body can increase if taken with strong CYP3A4 inhibitors like ketoconazole or grapefruit juice.
- Entocort is not suitable for use as a long-term replacement for systemic steroids because its action is primarily localized.
Avoid Entocort (Budesonide ER) If
- You should avoid taking Entocort if you are allergic to budesonide or any of its components.
- It should also be avoided if you are taking strong CYP3A4 inhibitors without medical supervision, or if you have active infections such as fungal, bacterial, or viral illnesses, or untreated tuberculosis.
- Pregnant or breastfeeding women should only use this medication if the potential benefits outweigh the risks, and only under medical guidance.
