Canasa (Mesalamine or Mesalazine)

Canasa is called Salofalk in Euope

Information about Canasa (Mesalamine or Mesalazine)

Canasa is a prescription medication that contains mesalamine (also known as mesalazine), an anti-inflammatory drug used primarily to treat inflammatory bowel diseases (IBD), such as ulcerative colitis. 

Mesalamine works locally in the colon to reduce inflammation and manage symptoms associated with these conditions. Canasa is specifically formulated as a suppository, designed for local treatment of inflammation in the rectum and lower part of the colon.

Product Highlights

• Specifically targets inflammation in the colon and rectum.
• Delivered via suppository, which allows for direct application to the affected area.
• Used both for the maintenance of remission in ulcerative colitis and for the treatment of flare-ups.

Key Ingredient

• Mesalamine (Mesalazine)

Key Benefits

• Helps to alleviate symptoms of ulcerative colitis and other inflammatory bowel diseases by reducing inflammation in the colon.
• Provides targeted relief directly to the inflamed area, potentially reducing systemic side effects.
• Effective in relieving symptoms such as rectal bleeding, abdominal pain, and diarrhea associated with ulcerative colitis.

Direction of Use

• Medication should be administered rectally at a dose of 1000 mg once daily at bedtime, and this regimen should be followed for 3 to 6 weeks. The safety and effectiveness of extending the use beyond 6 weeks have not been confirmed. 

Safety Concerns

• May include rectal discomfort, abdominal pain, nausea, and diarrhea.
• Rare but serious side effects can include allergic reactions, kidney issues, or worsening of gastrointestinal symptoms. Seek medical attention if you experience symptoms like rash, swelling, severe abdominal pain, or signs of kidney problems (e.g., changes in urine output, blood in urine).
• Generally, mesalamine has few drug interactions, but always inform your healthcare provider of all medications and supplements you are taking.

Avoid Canasa (Mesalamine or Mesalazine) If

• You are allergic to mesalamine or any other components of the medication.
• Those with severe kidney impairment should avoid using mesalamine or use it under strict medical supervision due to the risk of kidney-related side effects.
• If you have active gastrointestinal bleeding, consult with your healthcare provider, as this may affect the suitability of mesalamine treatment.