Information about Zomig ZMT (Zolmitriptan)
Zomig ZMT is an oral medication used to treat acute migraine attacks in adults, with or without aura. It contains zolmitriptan, a serotonin receptor agonist (triptan) that works by narrowing the blood vessels around the brain and reducing inflammation, which helps alleviate the pain and other symptoms associated with migraines. Zomig ZMT is an orally disintegrating tablet that dissolves quickly in the mouth, providing a convenient option for patients who may have difficulty swallowing traditional tablets.
Product Highlights
- Zomig ZMT is used for:
- It is prescribed to treat active migraine attacks with or without aura. It helps relieve the symptoms of a migraine episode, including the headache and associated nausea, vomiting, and sensitivity to light and sound.
- Zomig ZMT is not used to prevent future migraines but is effective in managing the symptoms of an ongoing migraine attack.
Key Ingredient
Key Benefits
- Zomig ZMT works quickly to provide relief from migraine symptoms, often within 30 minutes of administration.
- As an orally disintegrating tablet, Zomig ZMT does not require water, making it easier for patients who cannot swallow pills or who need a quick-acting medication.
- It not only relieves the headache but also alleviates other migraine symptoms such as nausea, vomiting, and sensitivity to light and sound.
- The tablet dissolves quickly in the mouth, eliminating the need for water, which can be beneficial when a migraine sufferer is experiencing nausea or has difficulty drinking fluids.
- By effectively addressing the symptoms of acute migraines, Zomig ZMT helps patients resume daily activities sooner and minimizes migraine-related discomfort.
Direction of Use
- Zomig ZMT is taken as a single orally disintegrating tablet. It should be placed on the tongue, where it will dissolve within seconds and can be swallowed without water.
- The usual starting dose is 2.5 mg, which may be increased to 5 mg if needed. The maximum recommended dose is 10 mg in a 24-hour period. If the first dose does not relieve the migraine, a second dose can be taken after 2 hours, but no more than two doses should be taken in a 24-hour period.
- Zomig ZMT is for acute treatment of migraine attacks, not for prevention. It should be taken at the onset of a migraine episode.
- Ensure that adequate fluid intake is maintained, especially in the case of nausea.
Safety Concerns
- Zomig ZMT can cause vasoconstriction (narrowing of blood vessels), which may pose risks for people with heart problems such as coronary artery disease, uncontrolled high blood pressure, or a history of heart attack. It should be used with caution in such individuals.
- When combined with other medications that affect serotonin levels (e.g., SSRIs, SNRIs, MAO inhibitors), there is a risk of serotonin syndrome, a potentially life-threatening condition. Symptoms include agitation, confusion, hallucinations, fast heart rate, high blood pressure, fever, muscle rigidity, and twitching.
- Frequent use of Zomig ZMT can lead to medication overuse headaches (MOH), where the headaches worsen with increasing use of migraine medications.
- In some cases, patients may experience irritation in the mouth or throat after taking the disintegrating tablet.
- Common side effects include dizziness, dry mouth, drowsiness, or a mild tingling sensation. These effects generally resolve shortly after the medication is absorbed.
- Zomig ZMT is classified as a Category C medication by the FDA during pregnancy, meaning its safety in pregnant women is not fully established. It should be used during pregnancy only if the potential benefits are greater than the potential risks to the fetus. Zolmitriptan may also pass into breast milk, so it should be used with caution in breastfeeding women.
- Zomig ZMT should be used with caution in individuals with liver or kidney problems, and dosage adjustments may be necessary.
Avoid Zomig ZMT (Zolmitriptan) If
- You have a history of heart disease, including coronary artery disease, heart attack, high blood pressure, or angina.
- You have a history of stroke or a transient ischemic attack (TIA).
- You are taking monoamine oxidase inhibitors (MAOIs) or have used them within the last 14 days.
- You are allergic to zolmitriptan or any of its ingredients.
- You have severe liver or kidney impairment.
- You have a history of hemiplegic migraine, basilar migraine, or migraine with prolonged aura.
- You are pregnant or breastfeeding, unless your healthcare provider has specifically recommended it.