Invega Sustenna (Paliperidone palmitate)

Invega Sustenna is called Xeplion in UK.  Both products are made by Janssen (Janssen-Cilag in the UK).  

The label dose in the United Kingdom is shown by a different measure.  The United Kingdom medicine shows the quantity of the active ingredient paliperidone while the the United States, the label shows the amount of paliperidone palmitate (the full chemical in its salt form).   Below is a comparison chart to show that the US versions and the UK versions contain the same amount of drug.

50 mg injection contains 78 mg paliperidone palmitate equivalent to 50 mg paliperidone.
75 mg injection contains 117 mg paliperidone palmitate equivalent to 75 mg paliperidone.
100 mg injection contains 156 mg paliperidone palmitate equivalent to 100 mg paliperidone.
150 mg injection contains 234 mg paliperidone palmitate equivalent to 150 mg paliperidone.

Prescription Invega Sustenna (called Xeplion in the UK) is a medicine used to treat schizophrenia and schizoaffective disorder once monthly by injection. Invega Sustenna can be taken either one its own or in combination with mood stabilizers, antidepressants or other medicine.

IInvega Sustenna is called an atypical antidepressant, in the same class as risperidone but causes less incidence of tremor or stiffness. Invega Sustenna works to restore balance of dopamine and serotonin in the brain.

Invega Sustenna an injection is given once monthly to adults by their healthcare provider, usually in the buttocks or arm.

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