Risperdal Consta (Risperidone)

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Brand Name : Risperdal Consta

Marketing Authorization Holder : Janssen-Cilag

Prescription Required

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No Generic Medicine available for this medicine.

Product Details

Risperdal Consta

Prescription Risperdal Consta (risperidone) is classified as an antipsychotic medicine which effects chemical levels in the brain. Risperdal Consta is a treatment for symptoms of bipolar disease and schizophrenia (when you see, hear, or feel things that are not truly there, or feel suspicious or confused). Risperdal Consta can help bring down these symptoms and prevent their return.

Risperdal Consta is used in patients that have been taking risperidone tablets (generic or brand Risperdal). After the first dose of Adults Risperdal Consta, it will take approximately 3 weeks to begin working. Store Risperdal Consta in a refrigerator, and only up to 7 days at room temperature prior to use.

Risperdal Consta is given by your healthcare provider in the muscle of your arm or buttock every 14 days, alternating injection sites.  Never have Risperdal Consta injected directly into a vein.

When switching from risperidone tablets to Risperdal Consta, your dose will depend on your previous risperidone therapy.  If you were taking 4mg or less risperidone daily, you will start with Risperdal Consta 25mg. If you were taking more than 4mg risperidone daily, your Risperdal Consta dose will likely be 37.5mg.  In case you are taking a different medicine for treatment, your physician will tell you what dose of Risperdal Consta to use. Always follow your physicians directions with Risperdal Consta. The maintenance dose of Risperdal Consta is given every 2 weeks at a dose up to 50mg.

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Information about Risperdal Consta (Risperidone)

Risperdal Consta is a long-acting injectable formulation of Risperidone, an atypical antipsychotic used to treat certain mental health conditions, including schizophrenia and bipolar disorder. Unlike the oral form of Risperdal, Risperdal Consta is administered via injection, typically every two weeks, to provide a consistent, controlled release of the medication. This helps improve patient compliance, as it eliminates the need for daily dosing.

Product Highlights

  • To treat symptoms such as delusions, hallucinations, and disorganized thinking, helping patients maintain better control over their condition.
  • For the management of manic or mixed episodes of bipolar disorder, often in combination with other medications for optimal symptom control.
  • It is also used for long-term maintenance therapy to help prevent relapses in schizophrenia and bipolar disorder after initial stabilization with oral medication.

Key Ingredient

  • Risperidone

Key Benefits

  • The long-acting injectable form of Risperdal Consta provides dosing every two weeks, helping to reduce the need for daily oral medication and enhance patient adherence. 
  • The consistent release of risperidone helps maintain stable blood levels, leading to more effective symptom management and reduced risk of relapse.
  • Risperdal Consta effectively controls symptoms of schizophrenia and bipolar disorder, such as hallucinations, delusions, and mood swings, leading to improved quality of life.
  • By eliminating the need for daily dosing, Risperdal Consta addresses issues related to non-adherence, which is common in patients with chronic psychiatric conditions.
  • It provides a reliable option for patients requiring long-term management of schizophrenia and bipolar disorder, reducing the frequency of clinic visits.

Direction of Use

  • Risperdal Consta is given as an intramuscular injection by a healthcare provider, usually every two weeks. The injection is usually given in the gluteal (buttocks) muscle.
  • The recommended starting dose is typically 25 mg every two weeks. Based on individual response and tolerance, the dose can be adjusted, generally increasing to a maximum dose of 50 mg every two weeks if needed.
  • Patients must be stabilized on oral risperidone before transitioning to Risperdal Consta to ensure the proper dosage and response to the medication.
  • Regular injections should be scheduled, as missing a dose may result in a relapse of symptoms.

Safety Concerns

  • Pain, redness, or swelling at the injection site can occur. Rotating injection sites is essential to reduce discomfort and prevent tissue damage. 
  • As with other antipsychotics, Risperdal Consta can cause extrapyramidal symptoms, such as tremors, stiffness, or involuntary movements. These should be monitored regularly.
  • Risperdal Consta can cause weight gain, elevated cholesterol levels, and changes in blood sugar, increasing the risk of diabetes and cardiovascular problems.
  • Some patients may experience drowsiness, dizziness, or sedation, particularly during the initial treatment phase or when the dose is adjusted.
  • A rare but serious side effect that may involve symptoms such as high fever, muscle stiffness, confusion, and autonomic instability. Immediate medical attention is required if these symptoms occur. 
  • Risperdal Consta can cause changes in heart rate and blood pressure, requiring monitoring, especially in patients with existing heart conditions.
  • Prolactin levels may increase with Risperdal Consta, leading to symptoms such as breast enlargement, lactation, and menstrual changes in women, and sexual dysfunction in both genders.

Avoid Risperdal Consta (Risperidone) If

  • If you have a known allergy to risperidone or any of the components in Risperdal Consta, you should avoid using it.
  • Patients with severe liver or kidney disease may need dose adjustments or may not be able to use Risperdal Consta safely.
  • If you have a history of NMS or other serious neurological side effects related to antipsychotic medications, Risperdal Consta should be avoided.
  • Patients with a history of heart issues, such as arrhythmias, heart failure, or low blood pressure, should use Risperdal Consta with caution due to the potential cardiovascular effects.
  • Risperdal Consta should only be used during pregnancy if the benefits outweigh the risks. It is generally not recommended during breastfeeding as it can pass into breast milk.
  • Risperdal Consta is not recommended for patients with dementia-related psychosis due to the increased risk of mortality in elderly patients with psychosis related to Alzheimer's disease.
This product requires special packaging to maintain its integrity during the shipping process. DO NOT USE THIS MEDICATION if the attached temperature indicator shows that the medication was exposed to temperatures below 2 degrees or above 8 degrees Celsius, and contact the pharmacy immediately.


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