Exelon (Rivastigmine)

Brand Options

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Brand Name : Exelon

Marketing Authorization Holder : Novartis

Prescription Required

 
 

Generic Option

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Generic Name : Rivastigmine

Manufactured By : Authorized UK and Indian Generic

Prescription Required

 
 

Product Details

Exelon

Information about Exelon (Rivastigmine)

Exelon is a medication that contains rivastigmine, a cholinesterase inhibitor, which works by increasing the levels of acetylcholine, a neurotransmitter involved in memory and learning. It is primarily used in the treatment of dementia-related conditions, including Alzheimer’s disease and Parkinson’s disease dementia. Rivastigmine helps improve cognition and functioning in individuals with these conditions, although it is not a cure. Exelon is available in both oral capsule and transdermal patch forms.

Product Highlights

  • Exelon is primarily used to treat mild to moderate dementia associated with Alzheimer’s disease and Parkinson’s disease dementia
  • It is designed to improve cognitive symptoms such as memory, thinking, and reasoning.
  • While it does not cure these diseases, Exelon can help slow the progression of symptoms and improve overall quality of life for individuals with these conditions.

Key Ingredient

  • Rivastigmine

Key Benefits

  • Exelon can offer several benefits to individuals with Alzheimer's and Parkinson's disease dementia, including:
  • Improvement in cognitive function, such as memory, attention, and problem-solving skills
  • Slowing of symptom progression, allowing individuals to maintain independence for a longer period
  • Improved overall functioning and quality of life
  • Convenient administration via patch form, which offers consistent medication delivery throughout the day and is easier for patients who have difficulty with oral medications.

Direction of Use

  • Oral Capsules/Oral Solution:
    Exelon should be taken with food to reduce the risk of gastrointestinal side effects. The usual starting dose is 1.5 mg twice daily, which can be increased gradually to 6 mg twice daily based on patient tolerance and medical advice. The dosage may be adjusted by the healthcare provider depending on the patient's response and tolerability.
  • Transdermal Patch:
    The patch is typically applied once daily to clean, dry, hairless skin, usually on the upper back, upper arm, or chest. The patch should not be cut, and a new patch should be applied to a different site each day, avoiding the same site for at least 14 days.

Safety Concerns

  • Gastrointestinal side effects, such as nausea, vomiting, and diarrhea, are common, especially when starting treatment or increasing the dose.
  • There is a risk of bradycardia (slow heart rate), particularly in elderly patients or those with preexisting heart conditions.
  • Exelon can also cause insomnia, dizziness, fatigue, and muscle weakness.
  • Skin reactions at the site of the patch, such as redness, itching, or irritation, can occur.
  • Caution is advised in patients with a history of seizures, liver or kidney disease, or gastrointestinal issues (e.g., ulcers or bleeding).
  • Patients should be monitored for changes in behavior, including agitation or depression.

Avoid Exelon (Rivastigmine) If

  • You are allergic to rivastigmine or any component of the Exelon formulation, including the adhesive used in the patch.
  • You have severe liver problems, as Exelon may worsen liver function in these individuals.
  • You have active gastrointestinal problems, such as ulcers or bleeding disorders.
  • You have a history of severe heart conditions, such as sick sinus syndrome, bradycardia, or heart block.
  • You are pregnant or breastfeeding unless advised otherwise by your healthcare provider.


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