Banzel (rufinamide) is called Inovelon in Europe. Both brands of rufinamide are manufactured by Eisai. In the United Kingdom this medicine is also available as 100mg, for patients requiring a lower or more specific dose of rufinamide.
Prescription Banzel is added to other seizure treatments to reduce severity and the frequency of many types of seizures in children over 1 year old and adults with Lennox-Gastaut syndrom (LGS).
Results of clinical studies have shown that Banzel reduces seizure severity by over 50%, frequency of tonic-atonic seizures by over 40% and total seizures by over 30%.
Banzel can be taken whole or split or crushed but should be taken with food. Banzel tablets should be stored in a dry place.
Banzel dosing in children will depend on age and weight and dosing usually begins as a low dose and is increased as they child gets used to the medicine and as the child grows. Adults usually begin with 400mg to 800mg Banzel divided into 2 daily doses, at the same time each day.
If you stop taking Banzel, it should be withdrawn slowly over time and only as per the physicians directions. Medicines, vitamins and herbs may interact with Banzel so be sure to inform the doctor of all medicine taken.
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Information about Banzel (Rufinamide):
Banzel, which contains the active ingredient Rufinamide, is primarily used to treat certain types of epilepsy, specifically Lennox-Gastaut syndrome (LGS) in patients aged 1 year and older. LGS is a severe form of epilepsy that is characterized by multiple types of seizures and developmental delays.
Rufinamide is the active ingredient in Banzel. It is a broad-spectrum antiepileptic drug that works by stabilizing the electrical activity in the brain, thus helping to reduce the frequency of seizures.
Product Highlights:
- Use in treating Lennox-Gastaut syndrome (LGS) in patients 1 year of age and older.
- Often used in combination with other anti-seizure medications to improve seizure control.
- Rufinamide, the active ingredient, helps to stabilize neuronal membranes and reduce seizure frequency by modulating voltage-gated sodium channels.
- Often used in conjunction with other antiepileptic drugs to enhance overall seizure control.
Key Ingredient:
- Rufinamide is the key ingredient in Banzel. It is a broad-spectrum antiepileptic drug that works by stabilizing the electrical activity in the brain, thus helping to reduce the frequency of seizures.
Key Benefits:
- Helps in reducing the frequency of seizures associated with Lennox-Gastaut syndrome.
- Generally well-tolerated with a side effect profile that is manageable for many patients.
- Available in multiple forms, including tablets and oral suspension, allowing for flexible dosing adjustments.
Directions for Use:
- Should be taken orally with a full glass of water. They can be swallowed whole or broken into halves or quarters if necessary.
- Measured using the provided dosing syringe and should be shaken well before each use.
- The dosage is typically individualized based on the patient's condition, response to treatment, and any side effects. It is essential to follow the prescribing physician’s dosage instructions closely.
Safety Concern:
- Common side effects include dizziness, drowsiness, headache, and nausea. More severe side effects can include mood changes, coordination problems, or rash.
- Regular monitoring by a healthcare provider is important to adjust the dosage as needed and to check for any potential adverse effects.
Avoid Banzel (Rufinamide) If:
- The patient has a known hypersensitivity or allergy to Rufinamide or any of the other components in Banzel.
- Use with caution or avoid if the patient has severe liver dysfunction, as Rufinamide is metabolized in the liver and may require dosage adjustments.
- Caution is needed if the patient is taking medications that affect the liver enzyme systems (like some antiepileptic drugs or certain other medications), as they can interact with Rufinamide and affect its efficacy and safety.
