Information about Depakote (Divalproex)
Depakote is a prescription medication used primarily as an anticonvulsant and mood stabilizer. It is frequently prescribed to manage seizure disorders, stabilize mood in bipolar disorder, and prevent migraines. Divalproex is a compound of valproic acid and is designed to release the active ingredient gradually, providing therapeutic benefits over an extended period.
Product Highlights
- Treatment of various types of seizures including generalized tonic-clonic seizures, complex partial seizures, and absence seizures.
- Controlling manic episodes related to bipolar disorder.
- Used to reduce the frequency of migraine attacks (off-label use).
Key Ingredient
Key Benefits
- Helps decrease both the frequency and severity of seizures in epilepsy.
- Effective in stabilizing mood and controlling manic episodes in bipolar disorder.
- Reduces the frequency of migraines when used for prophylaxis.
Direction of Use
- The dosage varies based on the condition being treated and patient-specific factors. Typical initial doses are around 500 mg to 1000 mg per day, which may be adjusted according to clinical response and blood levels.
- Take Depakote orally with or without food. Extended-release tablets should be swallowed whole; do not crush or chew.
- The oral suspension should be shaken well before use and measured with the provided dosing device.
Safety Concerns
- May include nausea, vomiting, drowsiness, dizziness, and tremors. Weight gain and gastrointestinal upset are also possible.
- Risk of liver toxicity, pancreatitis, and teratogenic effects (potential to cause birth defects). Regular monitoring of liver function and blood levels is necessary.
- Regular blood tests are recommended to monitor liver function, blood levels of divalproex, and complete blood counts.
Avoid Depakote (Divalproex) If
- You have a known hypersensitivity to Divalproex Sodium or any of its components.
- Avoid use if you have severe liver impairment or active liver disease due to the risk of liver toxicity.
- Depakote is associated with a high risk of birth defects and should be avoided during pregnancy unless absolutely necessary and prescribed by a healthcare provider.
- Avoid use if you have a history of pancreatitis or significant pancreatic issues.