Depakote (Divalproex)

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Brand Name : Depakote

Marketing Authorization Holder : SANOFI

Prescription Required

 
 
No Generic Medicine available for this medicine.

Product Details

Depakote

Information about Depakote (Divalproex)

Depakote is a prescription medication used primarily as an anticonvulsant and mood stabilizer. It is frequently prescribed to manage seizure disorders, stabilize mood in bipolar disorder, and prevent migraines. Divalproex is a compound of valproic acid and is designed to release the active ingredient gradually, providing therapeutic benefits over an extended period.

Product Highlights

  • Treatment of various types of seizures including generalized tonic-clonic seizures, complex partial seizures, and absence seizures.
  • Controlling manic episodes related to bipolar disorder.
  • Used to reduce the frequency of migraine attacks (off-label use).

Key Ingredient

  • Divalproex 

Key Benefits

  • Helps decrease both the frequency and severity of seizures in epilepsy.
  • Effective in stabilizing mood and controlling manic episodes in bipolar disorder.
  • Reduces the frequency of migraines when used for prophylaxis.

Direction of Use

  • The dosage varies based on the condition being treated and patient-specific factors. Typical initial doses are around 500 mg to 1000 mg per day, which may be adjusted according to clinical response and blood levels.
  • Take Depakote orally with or without food. Extended-release tablets should be swallowed whole; do not crush or chew. 
  • The oral suspension should be shaken well before use and measured with the provided dosing device.

Safety Concerns

  • May include nausea, vomiting, drowsiness, dizziness, and tremors. Weight gain and gastrointestinal upset are also possible.
  • Risk of liver toxicity, pancreatitis, and teratogenic effects (potential to cause birth defects). Regular monitoring of liver function and blood levels is necessary.
  • Regular blood tests are recommended to monitor liver function, blood levels of divalproex, and complete blood counts.

Avoid Depakote (Divalproex) If

  • You have a known hypersensitivity to Divalproex Sodium or any of its components.
  • Avoid use if you have severe liver impairment or active liver disease due to the risk of liver toxicity.
  • Depakote is associated with a high risk of birth defects and should be avoided during pregnancy unless absolutely necessary and prescribed by a healthcare provider.
  • Avoid use if you have a history of pancreatitis or significant pancreatic issues.


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